Green factory: plants as bioproduction platforms for recombinant proteins. (Special Issue: Production of recombinant proteins.)

Xu J. F.; Dolan M. C.; Medrano G.; Cramer C. L.; Weathers P. J.

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Green factory: plants as bioproduction platforms for recombinant proteins. (Special Issue: Production of recombinant proteins.)

机译：绿色工厂：植物作为重组蛋白的生物生产平台。（特刊：重组蛋白的生产。）

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Molecular farming, long considered a promising strategy to produce valuable recombinant proteins not only for human and veterinary medicine, but also for agriculture and industry, now has some commercially available products. Various plant-based production platforms including whole-plants, aquatic plants, plant cell suspensions, and plant tissues (hairy roots) have been compared in terms of their advantages and limits. Effective recombinant strategies are summarized along with descriptions of scalable culture systems and examples of commercial progress and success.

机译：长期以来，分子耕作一直被认为是一种生产有价值的重组蛋白的战略，不仅可用于人畜和兽药，而且还可用于农业和工业，现在已经有一些商品化产品。比较了各种基于植物的生产平台，包括整株植物，水生植物，植物细胞悬浮液和植物组织（毛状根）的优势和局限性。总结了有效的重组策略以及可扩展培养系统的描述以及商业进步和成功的例子。

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来源
《Biotechnology Advances: An International Review Journal》 |2012年第5期|共14页
作者
Xu J. F.; Dolan M. C.; Medrano G.; Cramer C. L.; Weathers P. J.;
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原文格式 PDF
正文语种 eng
中图分类生物工程学（生物技术）;
关键词
Molecular farming; Plant-made recombinant proteins; Transgenic plants; Plant cell culture; Microalgae; Moss; Hairy roots; Duckweed;

机译：分子耕作;植物重组蛋白;转基因植物;植物细胞培养;微藻;苔藓;多毛根;浮萍;

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1. Green factory: plants as bioproduction platforms for recombinant proteins. (Special Issue: Production of recombinant proteins.) [J] . Xu J. F., Dolan M. C., Medrano G., Biotechnology Advances: An International Review Journal . 2012,第5期

机译：绿色工厂：植物作为重组蛋白的生物生产平台。（特刊：重组蛋白的生产。）
2. Production of recombinant proteins by filamentous fungi. (Special Issue: Production of recombinant proteins.) [J] . Ward O. P. Biotechnology Advances: An International Review Journal . 2012,第5期

机译：丝状真菌生产重组蛋白。（特刊：重组蛋白的生产。）
3. Recovery and purification of plant-made recombinant proteins. (Special Issue: Foreign protein production using plant cells: opportunities and challenges.) [J] . Wilken L. R., Nikolov Z. L. Biotechnology Advances: An International Review Journal . 2012,第2期

机译：植物重组蛋白的回收和纯化。（特刊：利用植物细胞生产外来蛋白质：机遇与挑战。）
4. Monitoring bacterial processes by Fourier transform infrared spectroscopy: Helicobacter pylori drug inactivation and plasmid bioproduction in recombinant Escherichia coli cultures [C] . Scholz Teresa, Lopes Vitor V., Calado Cecilia R. C. 1st Portuguese Meeting in Bioengineering . 2011

机译：通过傅里叶变换红外光谱监测细菌过程：幽门螺杆菌药物失活和重组大肠杆菌培养物中的质粒生物生产
5. Development of plant cell suspension cultures as a bioproduction platform for recombinant human therapeutic proteins [D] . Huang, Ting-Kuo 2009

机译：开发植物细胞悬浮培养物作为重组人治疗性蛋白质的生物生产平台
6. Humoral immune response against human cytomegalovirus (HCMV)-specific proteins after HCMV infection in lung transplantation as detected with recombinant and naturally occurring proteins. [O] . J van Zanten, M C Harmsen, M van der Giessen, 1995

机译：用重组蛋白和天然存在的蛋白检测到的肺移植中HCMV感染后针对人巨细胞病毒（HCMV）特异性蛋白的体液免疫应答。
7. Metabolic adaptation in transplastomic plants massively accumulating recombinant proteins. [O] . Julia Bally, Claudette Job, Maya Belghazi, 2011

机译：转基因植物中的代谢适应大量积累重组蛋白。

Green factory: plants as bioproduction platforms for recombinant proteins. (Special Issue: Production of recombinant proteins.)

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