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The PORTO study and the gestational age perspective of Doppler interrogation of IUGR fetuses

机译:PORTO研究和IUGR胎儿多普勒审讯的胎龄观点

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In the PORTO study,1 only 46% of the IUGR fetuses had an abnormal UA pulsatility index (PI); the mean gestational age at enrollment to the study was 30.1 weeks, but the mean gestational age at delivery was 37.8 weeks. With late IUGR near term and with normal umbilical PI, the best predictor of fetal adaptation to hypoxemia is the middle cerebral arteries (MCA) PI.1 Under these circumstances, only the MCA/UA (cerebroplacental) ratio may be of value in assessing fetal and neonatal risks.4 If Doppler interrogation is put into a gestational perspective, it is obvious that this cohort of late IUGR, abnormal UA, and MCA Doppler velocimetry remain the strongest predictors of adverse outcome. However, it is important to acknowledge that this statement misses its point when deprived of its time domain.
机译:在PORTO研究中,1只有46%的IUGR胎儿的UA搏动指数(PI)异常;纳入研究的平均胎龄为30.1周,但分娩时的平均胎龄为37.8周。在IUGR较晚且脐带PI正常的情况下,胎儿对低氧血症适应的最佳预测指标是大脑中动脉(MCA)PI。1在这种情况下,只有MCA / UA(脑胎盘)比可能对评估胎儿具有价值。 4如果将多普勒讯问纳入妊娠观察,则很明显,这一晚期IUGR,异常UA和MCA多普勒测速仪的队列仍然是不良结局的最强预测指标。但是,重要的是要认识到,该语句在失去其时域时会失去其要点。

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