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首页> 外文期刊>Allergy >Ragweed sensitization in Europe - GA(2)LEN study suggests increasing prevalence.
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Ragweed sensitization in Europe - GA(2)LEN study suggests increasing prevalence.

机译：在欧洲豚草敏化-GA（2）LEN研究表明患病率增加。

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Common ragweed (Ambrosia artemisiifolia) is a highly allergenic plant species and the prime cause of allergic rhinitis in North America. Originally, in Europe, only Hungary has shown considerable spreading of Ambrosia since the early 1990s, when the abandonment of communist-style collective agriculture resulted in large uncultivated fields with con-current ragweed invasion. So far, ragweed sensiti-zations in other European countries were reported to be of only minorimportance with the highest rates registered in particular regions of Italy (Turin), the Netherlands (Geleen) and the UK (Norwich, 1).Here, results of a pan-European study from 16 centres in 13 European countries (GA2LEN; 01/2006-07/2007) are presented. Data on immediate sensitizationwere collected by standard prick testing. The study population consisted of rou,-tine out-patients with allergic symptdms who presented to one of the study centres. Median age of the 2026 participants was 35 years (25%o: 22 years and 75%: 50 years), gender distribution comprised 57.9% female and 42.1% male participants. In total, extracts for 18 inhalant allergens including Ambrosia artemisiifolia (ALK-Abello, Hamburg, Germany) were tested on the volar forearm. Results were recorded after 15 min and regarded positive if the wheal diameter calculated (largest + perpendicular diameter of the wheal/2) was >3 mm. Statistical analysis was performed with stata 9.0 software (StataCorp LP, College Station, TX, USA). Data were standardized with regard to age and gender. As of biases of either frequency or age distribution, Belgium, Switzerland and Greece were omitted in the country-specific analysis to achieve maximum comparability of the data.
机译：豚草（Ambrosia artemisiifolia）是高度致敏的植物物种，是北美变应性鼻炎的主要原因。最初，在欧洲，自1990年代初以来，只有匈牙利才显示出大量的Ambrosia蔓延，当时放弃了共产主义式的集体农业，导致了大片未耕作的土地，同时发生豚草入侵。到目前为止，据报道在意大利（都灵），荷兰（Geleen）和英国（Norwich，1）的特定地区，豚草过敏的影响很小，但发病率最高。提出了来自13个欧洲国家/地区的16个中心的泛欧研究（GA2LEN; 01 / 2006-07 / 2007）。通过标准的点刺试验收集有关立即敏化的数据。研究人群由参加过敏症研究中心的例行常规门诊患者组成。 2026名参与者的中位年龄为35岁（25％o：22岁，75％：50岁），性别分布包括57.9％的女性参与者和42.1％的男性参与者。总体上，在掌侧前臂上测试了18种吸入性过敏原的提取物，包括青蒿（ALK-Abello，汉堡，德国）。 15分钟后记录结果，如果计算的风团直径（风团的最大+垂直直径/ 2）> 3 mm，则认为是阳性。使用stata 9.0软件（StataCorp LP，美国德克萨斯州大学城）进行统计分析。有关年龄和性别的数据已标准化。由于频率或年龄分布的偏见，在特定国家/地区的分析中忽略了比利时，瑞士和希腊，以实现数据的最大可比性。

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