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Discrimination between moderate and severe disease may be used in patients with either treated or untreated allergic rhinitis.

机译：在治疗或未治疗的过敏性鼻炎患者中，可以区分中度和重度疾病。

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BACKGROUND: Allergic rhinitis (AR) is a common disease with major socioeconomic burden and a significant impact on quality of life. Objective: The aim of this study was to discriminate between moderate and severe AR patients whether receiving treatment or not, using a modified criterion of allergic rhinitis and its impact on asthma (ARIA) classification. METHODS: The modified ARIA severity classification (J Allergy Clin Immunol, 120, 2007, 359) categorizes AR as mild (no items affected), moderate (1-3 items affected), and severe (all four items affected). We applied these criteria to 1666 treated and 1058 untreated AR patients and compared their symptoms total four-symptom score (T4SS) and quality of life (ESPRINT-15), according to their clinical severity. RESULTS: Allergic rhinitis clinical status was significantly worse (P < 0.001) in treated than in untreated patients. For both treated and untreated patients, T4SS and ESPRINT-15 Quality of life scores were significantly worse (P < 0.001) in severe than in moderate patients. CONCLUSIONS: The modified ARIA severity classification is a useful clinical tool to discriminate moderate from severe AR among both treated and untreated patients.
机译：背景：过敏性鼻炎（AR）是一种常见的疾病，具有重大的社会经济负担，并且对生活质量产生重大影响。目的：本研究的目的是使用变应性鼻炎及其对哮喘（ARIA）分类的影响的标准，区分中度和重度AR患者是否接受治疗。方法：改良的ARIA严重程度分类（J Allergy Clin Immunol，120，2007，359）将AR分为轻度（无影响项），中度（1-3项影响）和重度（所有四项影响）。我们将这些标准应用于1666例治疗和1058例未经治疗的AR患者，并根据他们的临床严重程度比较了他们的症状总四症状评分（T4SS）和生活质量（ESPRINT-15）。结果：与未治疗的患者相比，治疗的变应性鼻炎的临床状况明显较差（P <0.001）。对于接受治疗和未经治疗的患者，重度患者的T4SS和ESPRINT-15生活质量评分显着低于中度患者（P <0.001）。结论：改良后的ARIA严重程度分类是一种有用的临床工具，可将中度和重度AR区分为已治疗和未治疗患者。

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