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首页> 外文期刊>Allergy >House dust mite avoidance measures for perennial allergic rhinitis: An updated Cochrane systematic review
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House dust mite avoidance measures for perennial allergic rhinitis: An updated Cochrane systematic review

机译：多年生过敏性鼻炎的屋尘螨避免措施：最新的Cochrane系统评价

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Background: To assess the benefits and harms of measures designed to reduce house dust mite (HDM) exposure in the management of house dust mite-sensitive allergic rhinitis. Methods: Systematic review of randomized controlled trials was made, in which HDM control measures have been evaluated in comparison with placebo or other HDM avoidance measures, in patients with clinically proven allergic rhinitis. Results: Nine trials involving 501 participants satisfied the inclusion criteria. These trials have investigated the effectiveness of bedroom environmental control programmes involving the use of HDM impermeable bedding covers (n = 4), acaricides (n = 2), high-efficiency particulate air filters (n = 2) and, using a factorial design, acaricide and HDM impermeable bedding covers in isolation and combination (n = 1). Seven of the nine trials reported that, when compared with control, the interventions studied resulted in significant reductions in HDM load. Of the interventions studied to date, acaricides appear to be the most promising, although the findings from these studies need to be interpreted with care because of their methodological limitations. House dust mite impermeable bedding as an isolated intervention is unlikely to offer benefit. Conclusions: Trials have tended to be small and of poor methodological quality, making it difficult to offer any definitive recommendations. Interventions that achieve substantial reductions in HDM load may offer some benefit in reducing rhinitis symptoms. Isolated use of HDM impermeable bedding is unlikely to prove effective.
机译：背景：评估旨在减少屋尘螨（HDM）暴露在管理屋尘螨敏感性过敏性鼻炎中的措施的利弊。方法：对随机对照试验进行了系统评价，其中对临床证实的变应性鼻炎患者与安慰剂或其他避免HDM的措施进行了评估。结果：9项试验包括501名参与者，符合纳入标准。这些试验研究了卧室环境控制计划的有效性，这些计划涉及使用HDM不可渗透的床上用品（n = 4），杀螨剂（n = 2），高效微粒空气过滤器（n = 2），并采用析因设计，杀螨剂和HDM不可渗透的被褥隔离和组合使用（n = 1）。九项试验中的七项报告说，与对照相比，所研究的干预措施显着降低了HDM负荷。在迄今为止研究的干预措施中，杀螨剂似乎是最有前途的，尽管由于这些研究方法的局限性，需要仔细解释这些研究的发现。作为单独的干预措施，屋尘螨不可渗透的被褥不太可能带来好处。结论：试验规模较小，方法学质量较差，因此很难提出任何明确的建议。可以显着减少HDM负荷的干预措施可以减轻鼻炎症状。单独使用HDM防渗垫料不太可能有效。

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