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首页> 外文期刊>Allergy >Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA(2)LEN.
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Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA(2)LEN.

机译:鼻炎和哮喘中上呼吸道和下呼吸道的共同特征:ARIA更新,与GA(2)LEN合作。

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摘要

This update aimed to review the new evidence available to support or refute prior Allergic Rhinitis and its Impact on Asthma (ARIA) statements. A Medline search of publications between 2000 and 2005 was conducted, with articles selected by experts. New evidence supports previous ARIA statements, such as: (i) allergic rhinitis (AR) is a risk factor for asthma; (ii) patients with persistent rhinitis should be evaluated for asthma; (iii) most patients with asthma have rhinitis; (iv) a combined strategy should be used to treat the airways and (v) in low- to middle-income countries, a different strategy may be needed. The increased risk of asthma has also been found among sufferers from non-AR. Recent reports show AR is a global problem. Many studies demonstrated parallel increasing prevalence of asthma and rhinitis, but in regions of highest prevalence, it may be reaching a plateau. Factors associated with a reduced risk of asthma and AR have been identified, confirming previous findings of protection related to exposure to infections. Treatment of rhinitis with intranasal glucocorticosteroids, antihistamines, leukotriene antagonists or immunotherapy may reduce morbidity because of asthma. To take advantage of the paradigm of unified airways, there is a need to rationalize diagnosis and treatment to optimize management.
机译:此更新旨在审查可用于支持或驳斥先前的过敏性鼻炎及其对哮喘的影响(ARIA)陈述的新证据。在2000年至2005年之间对Medline的出版物进行了检索,并选择了专家选出的文章。新的证据支持以前的ARIA陈述,例如:(i)过敏性鼻炎(AR)是哮喘的危险因素; (ii)患有持续性鼻炎的患者应进行哮喘评估; (iii)大多数哮喘患者患有鼻炎; (iv)应该使用综合策略治疗气道,并且(v)在中低收入国家/地区,可能需要采用其他策略。在非AR患者中也发现哮喘风险增加。最近的报告显示,AR是一个全球性问题。许多研究表明,哮喘和鼻炎的患病率呈平行上升趋势,但在患病率最高的地区,可能达到平稳状态。已经确定了与哮喘和AR风险降低相关的因素,从而证实了先前与感染相关的保护作用的发现。鼻内使用糖皮质激素,抗组胺药,白三烯拮抗剂或免疫疗法治疗鼻炎可降低哮喘引起的发病率。为了利用统一气道的范例,需要合理化诊断和治疗以优化管理。

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