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Health economics of asthma: assessing the value of asthma interventions.

机译：哮喘的健康经济学：评估哮喘干预措施的价值。

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The aim of this systematic review was to summarize and assess the quality of asthma intervention health economic studies from 2002 to 2007, compare the study findings with clinical management guidelines, and suggest avenues for future improvement of asthma health economic studies. Forty of the 177 studies met our inclusion criteria. We assessed the quality of studies using The Quality of Health Economic Studies validated instrument (total score range: 0-100). Six studies (15%) had quality category 2, 26 studies (65%) achieved quality category 3, and the remaining eight (20%) studies were scored as the highest quality level, category 4. Overall, the findings from this review are in line with the Global Initiative for Asthma clinical guidelines. Many asthma health economic studies lacked appropriate long term time horizons to match the chronic nature of the disease and suffered from using effectiveness measures that did not capture all disease related risks and benefits. We recommend that new asthma simulation models: be flexible to allow for long term time horizons, focus on using levels of asthma control in their structure, and estimate both long term asthma specific outcomes like well-controlled time as well as generic outcomes such as quality adjusted survival.
机译：该系统评价的目的是总结和评估2002年至2007年间哮喘干预健康经济研究的质量，将研究结果与临床管理指南进行比较，并为将来改善哮喘健康经济研究提供途径。 177项研究中有40项符合我们的纳入标准。我们使用经质量卫生经济学研究验证的工具（总分范围：0-100）评估了研究质量。六项研究（15％）的质量类别为2，26项研究（65％）的质量类别为3，其余八项（20％）的研究被评为最高质量级别，类别4。符合全球哮喘倡议临床指南。许多哮喘健康经济学研究缺乏与疾病的慢性特征相适应的长期长期视野，并且因无法使用无法捕获所有疾病相关风险和益处的有效措施而遭受痛苦。我们建议使用新的哮喘模拟模型：灵活地考虑到长期时间跨度，专注于在结构中使用哮喘控制水平，并估算长期特定于哮喘的结局（如时间控制良好）以及一般结局（如质量）调整生存率。

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