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首页> 外文期刊>Allergy >Infrequent milk consumption plus being overweight may have great risk for asthma in girls.
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Infrequent milk consumption plus being overweight may have great risk for asthma in girls.

机译:不经常喝牛奶加上超重的女孩可能会患哮喘。

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BACKGROUND: Inadequate milk consumption and being overweight are each associated with asthma symptoms in children. Milk consumption has been inversely related to childhood overweight. Thus, being overweight may be a pathway or a confounder in milk-asthma relationship. A combination of both factors may be associated with greater risk of asthma than one factor alone. METHODS: This study included 246 children with allergist-diagnosed asthma and 477 nonasthmatic controls at the age of 8-10 years. Information on milk consumption during the last 12 months was obtained from questionnaires. Being overweight was defined as body mass index > or =85th percentile. Being overweight as a possible pathway or confounder was formally tested. The odds ratio (OR) for combined infrequent milk consumption and being overweight in asthmatic vs nonasthmatic children was determined in multivariate logistic regression analyses. RESULTS: There was a significant interaction between milk consumption and sex of the child in relation to asthma. Asthma was significantly associated with infrequent milk consumption in girls (crude OR 2.11, 95% CI 1.05-4.24) but not in boys. The asthma-milk relation in girls was neither mediated by being overweight (p(mediation tests) = 0.27) nor was the relationship confounded by being overweight (a 9% change in coefficient). Asthmatic girls had 3.6 times increased odds of having combination of infrequent milk consumption and being overweight than nonasthmatic girls (adjusted OR 3.64, 95% CI 1.18-11.24). Asthma was not associated with either factor or with absence of the other in girls. CONCLUSION: Infrequent milk consumption plus being overweight may have great risk for asthma in girls.
机译:背景:牛奶摄入不足和超重均与儿童哮喘症状有关。牛奶消费与儿童超重成反比。因此,超重可能是牛奶哮喘关系中的一种途径或混杂因素。与单独的一个因素相比,这两个因素的组合可能与更大的哮喘风险相关。方法:本研究纳入了246例经过敏症诊断为哮喘的儿童和477例8至10岁的非哮喘控制儿童。最近十二个月的牛奶消费信息是从问卷中获得的。超重定义为体重指数>或= 85%。正式测试了超重作为一种可能的途径或混杂因素。在多因素logistic回归分析中确定了哮喘和非哮喘儿童中不经常食用牛奶和超重的比值比(OR)。结果:与哮喘相关的牛奶摄入量与儿童性别之间存在显着的相互作用。哮喘与女孩不经常喝牛奶有显着相关性(粗OR 2.11,95%CI 1.05-4.24),而男孩则没有。女孩的哮喘与牛奶的关系既不是由超重引起的(p(中介试验)= 0.27),也没有因超重而引起混淆(系数变化9%)。哮喘女孩少喝牛奶和超重相结合的几率是非哮喘女孩的3.6倍(调整后OR 3.64,95%CI 1.18-11.24)。哮喘与女孩中的任何一个因素或其他因素均不相关。结论:少喝牛奶加超重可能会增加女孩患哮喘的风险。

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