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首页> 外文期刊>感染症学雑誌 >Usefulness of urinary antigen and sputum Gram stain for rapid diagnosis of pneumococcal respiratory infections
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Usefulness of urinary antigen and sputum Gram stain for rapid diagnosis of pneumococcal respiratory infections

机译：尿抗原和痰革兰斑的用性快速诊断肺炎球菌呼吸道感染

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摘要

We evaluated the usefulness of a rapid urinary antigen detection kit (Binax NOW) to detect Streptococcus pneumoniae in the early diagnosis of pneumococcal respiratory tract infections in 313 patients with presumptive respiratory tract infections. We compared results of this test with those of sputum Gram staining. Urinary antigen and sputum Gram staining were respectively positive in 37 and 36 of 57 patients with pneumococcal respiratory infections. The urinary antigen showed moderate positive rate of 64.9% and low false positive rate of 2.3%. The sputum Gram staining also showed moderate positive rate of 64.3% and low false positive rate of 3.5%. Pneumococcal antigen was more frequently detected in patients with severe pneumococcal infections (6/6) than those with mild (5/10) and moderate (26/41) infections. Of the 9 patients who had received antibiotics before testing, antigen was detected in 8 but positive results of sputum Gram stain were in 4. In conclusion, urinary antigen test is a useful test for early diagnosis of pneumococcal respiratory infections especially in adult patients with moderate or severe infections for whom demonstrative results of a sputum Gram stain is unavailable, even after commencement of antibiotic treatment.
机译：我们评估了快速尿抗原检测试剂盒（Binax）的有用性来检测313例推测呼吸道感染患者肺炎球菌呼吸道感染的早期诊断中的链球菌肺炎。我们将该试验结果与痰革氏染色的结果进行了比较。尿抗原和痰克染色分别在57例肺炎球菌呼吸道感染患者的37和36例中阳性。尿抗原显示中度阳性率为64.9％，低误率为2.3％。痰革氏染色也显示中等阳性率为64.3％，低假阳性率为3.5％。在严重的肺炎球菌感染（6/6）患者中更频繁地检测到肺炎球菌抗原，而不是温和（5/10）和中度（26/41）感染的患者。在测试前接受抗生素的9例患者中，在8中检测到抗原，但痰革兰氏染色的阳性结果为4.总结，尿抗原试验是早期诊断肺炎球菌呼吸道感染的有用测试，特别是在中度成人患者中或者对于痰革兰氏染色的证据结果的严重感染是不可用的，即使在抗生素治疗开始后也是不可用的。

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