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Antimicrobial susceptibility testing of clinical isolates of Haemophilus influenzae derived from Japanese children

机译:日本儿童嗜血杆菌嗜血杆菌的临床分离株的抗菌易感性试验

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We examined the antimicrobial susceptibility testing of 1,024 Haemophilus influenzae isolates recovered from Japanese children. Percent distribution of beta-lactamase-negative ampicillin (ABPC)--resistant strain (BLNAR; ABPC-MIC > or = 4 microg/ml) was 15.0%. Prevalence of BLNAR increased remarkably from 12.7 to 22.1% in recent 4 years. Furthermore, the frequency of highly resistant strains (ABPC-MIC > or = 8 microg/ml) increased from 28.6 to 56.9% among BLNAR. Decreased susceptibility for cephems was observed in non-BLNAR strains including serotype b strain isolated from the cerebrospinal fluid.
机译:我们研究了从日本儿童中回收的1,024个血液渗透嗜血杆菌分离物的抗微生物易感性试验。 β-内酰胺酶阴性氨苄青霉素(ABPC)抗性菌株(BLNAR; ABPC-MIC> OR = 4 microg / mL)的百分比分布为15.0%。 近4年来,Blnar的患病率显着增加到22.1%至22.1%。 此外,高度抗性菌株(ABPC-MIC>或= 8微孔/ mL)的频率从BLNAR中的28.6%增加到56.9%。 在非Blnar菌株中观察到Cephems的易感性降低,包括从脑脊液中分离的血清型B菌株。

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