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首页> 外文期刊>日本耳鼻咽喉科学会会報 >Combination steroid and hyperbaric oxygenation therapy for sudden idiopathic sensorineural hearing loss
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Combination steroid and hyperbaric oxygenation therapy for sudden idiopathic sensorineural hearing loss

机译：组合类固醇和高压氧合疗法，用于突发特发性感觉障碍损失

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We retrospectively evaluated the efficacy of combination therapy with steroid and hyperbaric oxygenation for sudden idiopathic sensorineural hearing loss (SISNHL). Patients (n: 109; 111 ears) visited our clinic within 14 days from onset before receiving treatment between January 1999 and March 2003. Hearing loss was assessed based on criteria prepared by the Ministry of Health and Welfare Acute Severe Hearing Loss Study Group. Patients were distributed into Group I-95 patients who started treatment within 7 days from onset-, and Group II-14 patients who started treatment within 8-14 days from onset. We evaluated the outcome of therapy using grading established by The Research Committee on Acute Profound Deafness, Ministry of Health and Welfare, Japan. The complete recovery of hearing was worse in patients with severe hearing loss. It was 4.8% in grade 4a, 18.2% in grade 3a, 25% in grade 2a, 20.0% in grade 4b, 38.5% in grade 3b, and 66.7% in grade 2b. We studied the relationship between type of hearing loss and recovery after treatment. The complete recovery of hearing was most favorable in patients with low tone hearing loss, followed by those with middle tone hearing loss and those with horizontal hearing loss. These findings indicate that the type of hearing loss was the most significant determinant of SISNHL prognosis and course. Twenty patients with acute stage SISNHL had diabetes mellitus. The recovery of hearing was almost the same in those with and without diabetes mellitus. Recovery was complete in 32.4%, Niarked in 32.4%, and slight in 21.6%. In 13.5%, no change was observed. Our results and data from previous reports, involving more than 70 Japanese patients treated with steroids alone, suggest that combination therapy with steroid and hyperbaric oxygenation is effective for SISNHL.
机译：我们回顾性地评估了组合治疗与类固醇和高压氧合的疗效，用于突然特发性感觉症听力损失（SISNHL）。患者（N：109; 111只耳朵）在1999年1月至2003年3月期间接受待遇之前，在发病前的14天内访问了我们的诊所。根据卫生和福利急剧严重听证损失研究组编制的标准，评估了听证损失。将患者分为I-95款患者，从发病 - 和II-14岁开始在8-14天内开始治疗的患者。我们评估了日本卫生和福利部急性深深的耳聋研究委员会建立的评分的治疗结果。在严重听力损失的患者中，听力的完全恢复更糟。 4A级为4.8％，3A级的18.2％，2A级，2级，4级，38.5％的级别为38.5％，2B级为66.7％。我们研究了治疗后听力损失和恢复之间的关系。听力的完全恢复最有利于低音听力损失的患者，其次是具有中间色调听力损失的患者和水平听力损失的患者。这些发现表明，听力损失的类型是SisnHL预后和课程中最重要的决定因素。患有急性阶段的二十名患者患有糖尿病的糖尿病。在没有糖尿病的人和没有糖尿病的人中，听力的恢复几乎相同。恢复率为32.4％，占32.4％，略低于21.6％。在13.5％，没有观察到变化。我们的结果和数据来自以前的报告，涉及70多名日本患者单独治疗类固醇，表明用类固醇和高压氧合的联合治疗对SisNHL有效。

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