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A multicenter, randomized, controlled trial testing the effects of acupuncture on allergic rhinitis

机译：一项多中心，随机，对照试验，测试针灸对过敏性鼻炎的影响

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Background The aim of this study was to evaluate the efficacy and safety of acupuncture in the treatment for allergic rhinitis. Methods This study was a multicenter, randomized, parallel-controlled study. Participants were randomized to either the active acupuncture, sham acupuncture, or waitlist groups. The active and sham acupuncture groups received acupuncture treatment three times per week for 4 weeks. In the sham group, minimal acupuncture at nonacupuncture points was used. The waitlist group did not receive any acupuncture treatment. Results Of the 238 participants, 97, 94, and 47 individuals were assigned to the active acupuncture, sham acupuncture, and waitlist group, respectively. After the treatment, the difference in the total nasal symptom score (TNSS) was significantly reduced in the active acupuncture group compared with the sham acupuncture (difference: -1.03, 95% confidence interval [CI]: -1.96, -0.09, P = 0.03) and waitlist (difference: -2.49, 95% CI: -3.68, -1.29, P < 0.0001). The active acupuncture group exhibited a significant change in the total non-nasal symptom score (TNNSS) compared with the waitlist (difference: -0.78, 95% CI: -1.22, -0.34, P = 0.0002), but not the sham acupuncture group (difference; 0.15, 95% CI: -0.21, 0.5, P = 0.56). Both active and sham acupuncture treatments resulted in significant improvements in TNSS and TNNSS compared to baseline. Conclusion Active acupuncture showed a significantly greater effect on symptoms of allergic rhinitis than either sham acupuncture or no active treatment. The symptoms of allergic rhinitis decreased significantly after treatment in the both acupuncture and sham acupuncture groups. Acupuncture appears to be an effective and safe treatment for allergic rhinitis. ? 2012 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.
机译：背景技术这项研究的目的是评估针灸治疗过敏性鼻炎的有效性和安全性。方法该研究是一项多中心，随机，平行对照研究。参与者被随机分为活动针灸组，假针灸组或候补组。活动针灸组和假针灸组每周接受3次针灸治疗，共4周。在假手术组中，在非穴位使用最少的针灸。候补组未接受任何针灸治疗。结果238名参与者中，分别有97名，94名和47名个体被分配到活动针灸组，假针灸组和候补组。治疗后，与假针刺相比，活动针刺组的总鼻症状评分（TNSS）差异显着降低（差异：-1.03，95％置信区间[CI]：-1.96，-0.09，P = 0.03）和候补名单（差异：-2.49，95％CI：-3.68，-1.29，P <0.0001）。主动针灸组的总非鼻症状评分（TNNSS）与候补名单相比有显着变化（差异：-0.78，95％CI：-1.22，-0.34，P = 0.0002），而假针刺组则没有（差异; 0.15，95％CI：-0.21，0.5，P ＝ 0.56）。与基线相比，主动和假针灸治疗均导致TNSS和TNNSS的显着改善。结论主动针刺对变应性鼻炎症状的影响明显大于假针刺或不主动治疗。针灸组和假针灸组治疗后，过敏性鼻炎的症状均明显减轻。针灸似乎是治疗过敏性鼻炎的有效和安全的方法。 ？ 2012 John Wiley＆Sons A / S。由布莱克韦尔出版有限公司出版。

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