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Asthma Mortality Worldwide

机译:全球哮喘死亡率

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摘要

Over the last four decades, two patterns of asthma mortality can be seen: Epidemics, which occurred in a number of countries in the 1960s and in New Zealand in the 1970s-1980s, and gradual increases until the mid 1980s, and particular interest has centered on the possible role of asthma treatment in both these trends. Several explanations have been offered for the rise in asthma mortality: Increasing severity and prevalence of asthma, failure of management, and reactions to asthma medications [1]. Fortunately, from the 1990s until now, the rate of asthma mortality, global and age-adjusted for the range 5-34 years, shows a gradually decreasing tendency in most countries around the world. It has been hypothesized that better care, particularly the use of inhaled steroids, may be at least partly responsible for this trend. Studies have shown that prescribed inhaled steroids are associated with a lower rate of hospital admissions for asthma. More recently, inhaled steroids were reported to be associated with a lower rate of asthma deaths. The association between inhaled steroids and a decreased risk of asthma death was confined to patients receiving at least six canisters of inhaled steroids per year, among whom there was only one asthma death [2].
机译:在过去的四十年中,可以看到两种哮喘死亡率模式:流行病,在1960年代的许多国家和1970到1980年代的新西兰发生,并在1980年代中期之前逐渐增加,特别引起了人们的关注。在这两种趋势中哮喘治疗的可能作用。对于哮喘死亡率的上升,有几种解释:哮喘的严重程度和患病率增加,管理失败以及对哮喘药物的反应[1]。幸运的是,从1990年代到现在,全球范围内和年龄调整(5-34岁)的哮喘死亡率在全球大多数国家中呈逐渐下降的趋势。据推测,更好的护理,尤其是吸入性类固醇的使用,可能至少部分是造成这一趋势的原因。研究表明,处方吸入类固醇与哮喘住院率较低有关。最近,据报道吸入类固醇与哮喘死亡率降低有关。吸入类固醇与降低的哮喘死亡风险之间的相关性仅限于每年至少接受六罐吸入性类固醇的患者,其中只有一名哮喘死亡[2]。

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