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Urticaria, Angioedema, and Their Psychogenic Triggers: A Clinical Approach

机译:荨麻疹,血管性水肿及其心理诱因:一种临床方法

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Background: It is not always easy to distinguish between psychological triggers and other etiologies (food, drugs, etc.) of urticaria and/or angioedema. Urticaria/angioedema of a purely psychogenic etiology has been contested in the literature. Methods/Data base: This article reviews published data and author's own studies made between 1979 and 2006, focused on psychologically triggered urticaria/angioedema and on personality traits of urticaria patients. Results: Studies do not confirm the existence of urticaria/angioedema exclusively induced by psychological factors, but confirm that psychological etiology has a constant involvement in cholinergic urticaria and an optional role in triggering some forms of spontaneous acute or physical urticaria/angioedema, as well as in maintaining and aggravating chronic urticaria. About 32% of urticaria/angioedema can be triggered by psychological factors, alternately or associated with "common etiologic agents". Urticaria/angioedema with psychogenic triggers occurin patients with increased vulnerability to emotional distress (more frequently in females) and in cases of prolonged evolution of the disease. Conclusions: In such urticaria/angioedema patients, especially with chronic urticaria, it is advisable to search for psychological triggers and for certain psychiatric disorders, especially anxiety and depression. An approach by a team of specialists (including psychologists and psychiatrists) might have a positive effect on the evolution of the disease, as might adding antidepressants and anxiolytics to antihistamines.
机译:背景:区分荨麻疹和/或血管性水肿的心理触发因素和其他病因(食物,药物等)并不总是那么容易。纯粹的精神病因病引起的荨麻疹/血管性水肿已在文献中引起争议。方法/数据库:本文回顾了1979年至2006年之间发表的数据和作者自己的研究,重点是心理引发的荨麻疹/血管性水肿以及荨麻疹患者的人格特征。结果:研究并未证实仅由心理因素引起的荨麻疹/血管性水肿的存在,但证实了心理病因学一直参与胆碱能性荨麻疹,并且在触发某些形式的自发性急性或生理性荨麻疹/血管性水肿以及其他方面具有选择性作用维持和加重慢性荨麻疹。大约32%的荨麻疹/血管性水肿可以由心理因素触发,或者与“常见病因”相关。具有精神诱因的荨麻疹/血管性水肿发生在易受情绪困扰影响的患者中(女性更为常见)以及疾病发展时间较长的情况。结论:在这类荨麻疹/血管性水肿患者中,尤其是慢性荨麻疹患者,建议寻找心理诱因和某些精神疾病,尤其是焦虑和抑郁。一组专家(包括心理学家和精神科医生)采取的方法可能会对疾病的发展产生积极影响,可能在抗组胺药中添加抗抑郁药和抗焦虑药。

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