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首页> 外文期刊>American Journal of Physiology >Longitudinal strain quantitates regional right ventricular contractile function.
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Longitudinal strain quantitates regional right ventricular contractile function.

机译：纵向应变量化了局部右心室收缩功能。

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摘要

The assessment of contractile function of the right ventricle (RV) is an important clinical issue, but this remains difficult because of its complex anatomy and structure. We thought to investigate whether new Doppler-derived myocardial deformation indexes may quantify regional contractile RV function during varying loading conditions. In nine pigs, ultrasonic crystals were inserted longitudinally in the RV inflow and outflow tracts to assess regional contractile function. The same RV segments and the interventricular septum were imaged using apical echocardiographic views. Regional function was assessed using two parameters: 1) systolic strain (SS), representing the relative magnitude of segmental systolic shortening; and 2) its temporal derivative, peak systolic strain rate (SR), i.e., the maximal velocity of segmental shortening. Data were acquired at baseline and during partial pulmonary artery constriction (PAC) and inferior vena cava occlusion (IVCO). SS decreased significantly after PAC and IVCOin both the inflow and outflow tracts but only during IVCO in the septum. SR was less sensitive to loading variations in all segments. A significant correlation was found between SS values derived from sonomicrometry and myocardial Doppler in RV segments (r = 0.84, P < 0.001). Thus regional strain and SR provide complementary information on the heterogeneous RV contractile function and can be accurately and noninvasively quantified using Doppler myocardial imaging.
机译：右心室（RV）收缩功能的评估是一个重要的临床问题，但是由于其复杂的解剖结构和结构，这仍然很困难。我们考虑研究在变化的负荷条件下新的多普勒衍生的心肌变形指数是否可以量化局部收缩性右室功能。在9头猪中，将超声波晶体纵向插入RV流入和流出通道，以评估局部收缩功能。使用心尖超声心动图对相同的RV节段和室间隔进行成像。使用两个参数评估区域功能：1）收缩期应变（SS），代表节段性收缩期缩短的相对大小; 2）其时间导数，峰值收缩期收缩率（SR），即节段缩短的最大速度。在基线和部分肺动脉狭窄（PAC）和下腔静脉阻塞（IVCO）期间获取数据。 PAC和IVCO在流入和流出道后SS均显着下降，但仅在隔垫的IVCO期间。 SR对所有分段中的负载变化不太敏感。在体视测定法得出的SS值与RV节段中的心肌多普勒之间存在显着相关性（r = 0.84，P <0.001）。因此，区域应变和SR提供了关于异质性RV收缩功能的补充信息，并且可以使用多普勒心肌成像准确且无创地定量。

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