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Computed tomography scans in the evaluation of patients with olfactory dysfunction.

机译:计算机断层扫描可评估嗅觉功能障碍患者。

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BACKGROUND: The necessity of computed tomography (CT) scans of the olfactory cleft and the sinuses in patients presenting with olfactory dysfunction is a matter of debate. This study aimed to investigate the significance of CT scans for the diagnosis of olfactory loss and for therapeutic decisions. METHODS: This retrospective study included 137 consecutive patients presenting with the main complaint of olfactory loss. Standardized history; ear, nose, and throat examination; and olfactory tests were administered. In addition, a CT scan of the nasal sinuses was obtained. The assumed diagnosis (sinonasal disease [SND] or non-SND) was compared with the diagnosis when additionally considering results from the CT scan. RESULTS: CT scans suggested SND in 7/101 patients, without clinical evidence of its presence. In 12/36 patients with suspected SND-related olfactory loss, no signs of SND were detected in CT scans. CONCLUSION: CT scans are useful to diagnose conductive/inflammatory olfactory loss in patients suspected of non-SND, which may then justify a course with systemic steroids. Alternatively, considering low costs and rare side effects of a short course with steroids in selected patients, CT scans appear to be of clinical significance only when surgical treatment is contemplated or where the use of systemic corticosteroids is not possible.
机译:背景:存在嗅觉功能障碍的患者中,对嗅裂和鼻窦进行计算机断层扫描(CT)的必要性尚有争议。这项研究旨在调查CT扫描对嗅觉丧失的诊断和治疗决策的意义。方法:这项回顾性研究包括137例患者,主要表现为嗅觉丧失。标准化的历史记录;耳鼻喉检查;并进行嗅觉测试。另外,获得了鼻窦的CT扫描。当另外考虑CT扫描的结果时,将假定的诊断(鼻窦疾病[SND]或非SND)与该诊断进行比较。结果:CT扫描提示7/101名患者存在SND,但没有临床证据表明存在SND。在怀疑与SND相关的嗅觉丧失的12/36患者中,CT扫描未发现SND征象。结论:CT扫描可用于诊断怀疑为非SND的患者的传导性/炎症性嗅觉丧失,这可能为全身性激素治疗提供了依据。另外,考虑到成本低廉以及在选定的患者中短期使用类固醇激素的副作用少,CT扫描仅在考虑进行手术治疗或无法使用全身性皮质类固醇激素时才具有临床意义。

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