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首页> 外文期刊>American journal of rhinology >Middle meatus bacteriology of acute rhinosinusitis in patients after irradiation of nasopharynx.
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Middle meatus bacteriology of acute rhinosinusitis in patients after irradiation of nasopharynx.

机译:鼻咽照射后患者急性鼻-鼻窦炎的中耳细菌学。

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摘要

BACKGROUND: Patients who undergo radiotherapy for nasopharyngeal carcinoma (NPC) tend to suffer from rhinosinusitis because irradiation causes damage to sinonasal tissue; however, their bacteriology is lacking in the literature. The aim of this study was to determine the bacteriology and antibiotic resistance in acute rhinosinusitis (ARS) of these patients. METHODS: We collected nasal purulent discharge for bacteriology and antibiotic susceptibility tests in irradiated NPC patients with ARS. Middle meatus discharge was aspirated for culture with endoscopic assistance. RESULTS: A total of 33 episodes of ARS were documented in 25 patients. Staphylococcus aureus comprised 42% of all aerobes. Thirty-six percents of aerobic isolates were Gram-negative bacilli. Peptostreptococcus micros and Veillonella spp were the most frequently isolated anaerobes. CONCLUSION: The bacteriology in irradiated NPC patients with ARS was distinctive in the following: first, the most common pathogen was S. aureus; second, frequently isolated Gram-negative bacilli and anaerobes; and third, polymicrobial infections. The beta-lactamase-producing pathogens were highly prevalent.
机译:背景:接受放射治疗鼻咽癌(NPC)的患者倾向于患鼻-鼻窦炎,因为放射线会损伤鼻窦组织。但是,文献中缺乏它们的细菌学。这项研究的目的是确定这些患者的急性鼻鼻窦炎(ARS)的细菌学和抗生素耐药性。方法:我们收集了鼻腔脓性分泌物,用于接受辐射的NPC的ARS患者的细菌学和抗生素敏感性试验。在内窥镜辅助下抽吸中鼻道分泌物进行培养。结果:25例患者共记录了33例ARS。金黄色葡萄球菌占所有需氧菌的42%。有氧菌中有百分之三十六是革兰氏阴性杆菌。微小链球菌和Veillonella spp是最常分离的厌氧菌。结论:经辐照的NPC鼻咽癌患者的细菌学特点如下:首先,最常见的病原体是金黄色葡萄球菌;第二,经常分离出革兰氏阴性杆菌和厌氧菌;第三,微生物感染。产生β-内酰胺酶的病原体高度流行。

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