...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>American journal of therapeutics >Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction.
【24h】

Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction.

机译：通过组织多普勒超声心动图评估左室舒张功能与激素替代疗法有关的绝经后女性舒张功能障碍。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The objective of this study was to evaluate the effect of hormone replacement therapy (HRT) regimens on left ventricular diastolic function by using mitral pulsed wave Doppler (MPWD) and tissue Doppler velocities (TDE). Seventy-eight postmenopausal women with normotensive and impaired diastolic left ventricular filling were included in the study. All the patients began a six-cycle HRT course. This formulation consisted of E2 valerate plus Medroxy progesterone acetate (MPA). Left ventricular diastolic function at rest was evaluated by M-mode, two-dimensional, MPWD and TDE in 78 postmenopausal women with normal blood pressure before the treatment for 6 months of HRT. The M-mode, two-dimensional, and MPWD parameters assessed were heart rate, systolic blood pressure, diastolic blood pressure, left ventricular mass index, ejection fraction of the left ventricle (EF), septal (IVS) and posterior wall (PW) thickness, left ventricular end-systolic (LVESD) and end-diastolic (LVEDD) diameter, left atrial diameter, peak early diastolic velocity (E), peak atrial velocity (A), E/A ratio, E acceleration time, E deceleration time, diastolic filling period, and isovolumic relaxation time (IVRT). The TDE parameters assessed were peak early diastolic velocity (E'), peak late diastolic velocity (A'), peak systolic velocity, E'/A' ratio, E' acceleration time, E' deceleration time, IVRT', and E/E' ratio. Quantitative data were analyzed using Student t test. Among the MPWD parameters, peak A velocity, E deceleration time, and IVRT significantly decreased, while peak E velocity and E/A ratio increased after a 6-month treatment. From the point of TDE parameters, E' velocity and E'/A' ratio increased, while A' velocity, E' deceleration time, E/E' ratio and IVRT' decreased. Some MPWD and TDE parameters were partially reversed after HRT. TDE velocities and especially E/E' ratio may provide better and true information of the diastolic function. TDE parameters were independent from the preload and did not produce pseudonormal pattern. HRT may cause increase in the blood volume and produce pseudonormal pattern in transmitral flow. In that case, TDE may be a beneficial method for evaluation of diastolic function.
机译：这项研究的目的是通过使用二尖瓣脉冲波多普勒（MPWD）和组织多普勒速度（TDE）来评估激素替代疗法（HRT）方案对左心室舒张功能的影响。该研究纳入了78名绝经后女性，其血压正常且舒张期左心室充盈受损。所有患者均开始了六个周期的HRT疗程。该配方由戊二酸E2加上醋酸甲羟孕酮（MPA）组成。在接受HRT治疗6个月之前，通过M型，二维，MPWD和TDE对78名血压正常的绝经后妇女进行了静息时左心室舒张功能的评估。评估的M型，二维和MPWD参数为心率，收缩压，舒张压，左心室质量指数，左心室射血分数（EF），间隔（IVS）和后壁（PW）厚度，左心室收缩末期（LVESD）和舒张末期（LVEDD）直径，左心房直径，最大舒张早期速度（E），最大心房速度（A），E / A比，E加速时间，E减速时间，舒张期充盈期和等容舒张时间（IVRT）。评估的TDE参数为舒张早期峰值速度（E'），舒张晚期峰值速度（A'），收缩期峰值速度，E'/ A'比，E'加速时间，E'减速时间，IVRT'和E / E'比。使用学生t检验分析定量数据。在MPWD参数中，治疗6个月后，峰值A速度，E减速时间和IVRT显着降低，而峰值E速度和E / A比增加。从TDE参数的角度来看，E'速度和E'/ A'比增加，而A'速度，E'减速时间，E / E'比和IVRT'减少。 HRT后，某些MPWD和TDE参数被部分反转。 TDE速度，尤其是E / E'比可提供更好和真实的舒张功能信息。 TDE参数与预载无关，并且不会产生伪正态模式。 HRT可能导致血容量增加，并在传递流中产生伪正常模式。在这种情况下，TDE可能是评估舒张功能的有益方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号