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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Validation of the Ectasia Risk Score System for preoperative laser in situ keratomileusis screening.
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Validation of the Ectasia Risk Score System for preoperative laser in situ keratomileusis screening.

机译：Ectasia风险评分系统用于术前激光原位角膜磨镶术筛查的验证。

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摘要

PURPOSE: To validate the Ectasia Risk Score System for identifying patients at high risk for developing ectasia after laser in situ keratomileusis (LASIK). DESIGN: Retrospective case-control study. METHODS: Fifty eyes that developed ectasia and 50 control eyes with normal postoperative courses after LASIK were analyzed and compared using the previously described Ectasia Risk Score System, which assigns points in a weighted fashion to the following variables: topographic pattern, predicted residual stromal bed (RSB) thickness, age, preoperative corneal thickness (CT), and manifest refraction spherical equivalent (MRSE). RESULTS: In this series, 46 (92%) eyes with ectasia were correctly classified as being at high risk for the development of ectasia, while three (6%) controls were incorrectly classified as being at high risk for ectasia (P < 1 x 10(-10)). Significantly more eyes were classified as high risk by the ectasia risk score than by traditional screening parameters relying on abnormal topography or RSB thickness less than 250 micro (92% vs 50%; P < .00001). There was no difference in the sensitivity or specificity of the Ectasia Risk Score System in the population from which it was derived and this independent population of ectasia cases and controls. CONCLUSIONS: The Ectasia Risk Score System is a valid and effective method for detecting eyes at risk for ectasia after LASIK and represents a significant improvement over previously utilized screening strategies.
机译：目的：验证Ectasia风险评分系统，以识别激光原位角膜磨镶术（LASIK）后发展为扩张性疾病的高风险患者。设计：回顾性病例对照研究。方法：使用先前描述的Ectasia风险评分系统分析和比较LASIK后发展为扩张期的50只眼和50例术后正常眼的对照眼，该系统以加权方式将点分配给以下变量：地形图，预测的残余基质床（ RSB）厚度，年龄，术前角膜厚度（CT）和明显屈光球当量（MRSE）。结果：在这个系列中，有46个（92％）的扩张性眼被正确归类为发展为高风险的眼睛，而三个（6％）的对照被错误地归为具有扩张性的高风险（P <1 x 10（-10））。与基于依赖于异常地形或RSB厚度小于250 micro的传统筛查参数的传统筛查参数相比，通过扩张性风险评分被分类为高风险的眼睛要多得多（92％对50％; P <.00001）。 Ectasia风险评分系统的敏感性或特异性在其来源人群以及独立的ectasia病例和对照人群中没有差异。结论：Ectasia风险评分系统是检测LASIK术后有水肿风险的眼睛的有效方法，与以前使用的筛查策略相比，具有显着改善。

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