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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Clinical features of immune rejection after corneoscleral transplantation.
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Clinical features of immune rejection after corneoscleral transplantation.

机译：角膜巩膜移植后免疫排斥反应的临床特征。

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PURPOSE: To summarize the clinical features of immune rejection after corneoscleral transplantation. DESIGN: A retrospective, noncomparative, observational case series. METHODS: Patients who received corneoscleral transplantation because of whole corneal ulcer or corneal perforation at Shandong Eye Institute from July 1, 2003 through July 31, 2005 were included. Fourteen patients (14 eyes) with immune rejection but not recurrence or other complications were reviewed, including ocular vision, rejection onset time, symptoms, and characteristics. RESULTS: The average rejection time in the 14 eyes was 35 days. The rejection arose rapidly, and the mean best-corrected visual acuity decreased to counting fingers or hand movements. Circular limbal congestion and edema developed with circuitous and dilatational vessels. Whole graft edema and Descemet membrane folds were present, but no epithelial rejection line, endothelial rejection line, or keratic precipitate were observed. The average intraocular pressure (IOP) dropped from 13.6 mm Hg to 7.4 mm Hg. Seven eyes had shallow anterior chambers (AC). Retinal and choroidal edema was observed in five eyes. CONCLUSIONS: The clinical features of immune rejection after corneoscleral transplantation include rapid onset of rejection, vision decrease, circular limbal congestion and edema with circuitous and dilatational vessels, whole graft edema and shallow AC, low IOP, and no rejection line or keratic precipitate.
机译：目的：总结角膜巩膜移植后免疫排斥反应的临床特征。设计：回顾性，非比较性，观察性病例系列。方法：纳入2003年7月1日至2005年7月31日在山东省眼科研究所因全角膜溃疡或角膜穿孔而接受角膜巩膜移植的患者。回顾了14例（14眼）有免疫排斥反应但未复发或没有其他并发症的患者，包括眼视力，排斥反应发作时间，症状和特征。结果：14只眼的平均排斥时间为35天。排斥反应迅速出现，平均最佳矫正视力下降到计数手指或手的动作。圆形limb状充血和水肿出现circuit回和扩张血管。存在整个移植物浮肿和Descemet膜折叠，但未观察到上皮排斥线，内皮排斥线或角质沉淀。平均眼内压（IOP）从13.6毫米汞柱降至7.4毫米汞柱。七只眼的前房浅（AC）。在五只眼中观察到视网膜和脉络膜水肿。结论：角膜硬化移植后免疫排斥反应的临床特征包括排斥反应迅速发作，视力下降，角膜缘充血和水肿，circuit回和扩张血管，整个移植物水肿和浅AC，IOP低，无排斥线或角质沉淀。

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