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首页> 外文期刊>American Journal of Ophthalmology: The International Journal of Ophthalmology >Choroidal analysis in healthy eyes using swept-source optical coherence tomography compared to spectral domain optical coherence tomography
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Choroidal analysis in healthy eyes using swept-source optical coherence tomography compared to spectral domain optical coherence tomography

机译：与频谱域光学相干断层扫描相比，使用扫频光学相干断层扫描在健康眼睛中进行脉络膜分析

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? Purpose: To compare analyses of choroidal thickness and volume in healthy eyes measured concurrently with prototype long-wavelength swept-source optical coherence tomography (OCT) and commercially available spectral-domain optical coherence tomography (OCT) with and without enhanced depth imaging (EDI). ? Design: Prospective cross sectional study. ? Methods: The study included 19 healthy subjects (19 eyes), who were prospectively recruited to undergo 2 consecutive imaging sessions on the same randomly selected eye using spectral domain OCT and a prototype long-wavelength swept-source OCT. On spectral domain OCT, 2 line scans, 1 with and 1 without EDI, and 1 volumetric scan were obtained. On swept-source OCT, 1 line scan and 1 volumetric scan were obtained. Scan patterns on swept-source OCT were created to simulate those available on Cirrus HD-OCT to keep the time of image acquisition constant. Swept-source OCT volumetric scans were motion corrected using a novel registration algorithm. Choroidal thickness and volume were analyzed. ? Results: The choroidoscleral interface was clearly visualized in 19/19 (100%) of eyes imaged by swept-source OCT, compared to 14/19 (73.6%) and 13/19 (68.4%) eyes imaged by spectral domain OCT, with and without EDI, respectively. There was no significant difference in choroidal thickness measurements on the line scans obtained on either system (P = 0.10). Choroidal volume could not be assessed on volumetric scans from spectral domain OCT. Mean choroidal volume from swept-source OCT volumetric scans was 11.77 ± 3.13 mm3 (6.43 mm3-17.15 mm3). ? Conclusion: This is the first study that compares simultaneously a prototype long-wavelength swept-source OCT to a commercially available spectral domain OCT for a detailed analysis of choroid in healthy eyes. Swept-source OCT shows potential for better choroidal analysis. Studies using swept-source OCT in diseased eyes will further define this new technology's utility in chorioretinal diseases.
机译：？目的：比较采用原型长波长扫频光源光学相干断层扫描（OCT）和市售的光谱域光学相干断层扫描（OCT）并结合增强型深度成像（EDI）和不进行增强深度成像（EDI）的同时测量的健康眼睛中脉络膜厚度和体积的分析。 ？设计：前瞻性横断面研究。 ？方法：该研究包括19名健康受试者（19眼），他们被招募为使用光谱域OCT和原型长波扫描源OCT在同一只随机选择的眼睛上进行两次连续成像会议。在光谱域OCT上，获得了2条线扫描，其中1条带EDI和1条不带EDI，以及1条体积扫描。在扫描源OCT上，获得了1条线扫描和1条体积扫描。创建了扫描源OCT上的扫描图案以模拟Cirrus HD-OCT上可用的图案，以保持图像采集时间恒定。使用新型配准算法对扫频源OCT体积扫描进行了运动校正。分析脉络膜的厚度和体积。 ？结果：通过扫频源OCT成像的眼睛中有19/19（100％）的脉络膜巩膜界面清晰可见，相比之下，通过光谱域OCT成像的眼睛中有14/19（73.6％）和13/19（68.4％）眼，和没有EDI的情况。在任一系统上进行的线扫描中脉络膜厚度测量值均无显着差异（P = 0.10）。从频谱域OCT进行体积扫描无法评估脉络膜体积。来自扫描源OCT体积扫描的平均脉络膜体积为11.77±3.13 mm3（6.43 mm3-17.15 mm3）。 ？结论：这是第一项同时比较原型长波长扫频光源OCT和市售光谱域OCT的研究，以详细分析健康眼睛中的脉络膜。扫频OCT显示出更好的脉络膜分析潜力。在患病眼中使用扫频OCT的研究将进一步定义这项新技术在脉络膜视网膜疾病中的效用。

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