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The respiratory pyramid: From symptoms to disease in world trade center exposed firefighters

机译:呼吸金字塔:世界贸易中心暴露的消防员从症状到疾病

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Background: This study utilizes a four-level pyramid framework to understand the relationship between symptom reports and/or abnormal pulmonary function and diagnoses of airway diseases (AD), including asthma, recurrent bronchitis and COPD/emphysema in WTC-exposed firefighters. We compare the distribution of pyramid levels at two time-points: by 9/11/2005 and by 9/11/2010. Methods: We studied 6,931 WTC-exposed FDNY firefighters who completed a monitoring exam during the early period and at least two additional follow-up exams 9/11/2005-9/11/2010. Results: By 9/11/2005 the pyramid structure was as follows: 4,039 (58.3%) in Level 1, no respiratory evaluation or treatment; 1,608 (23.2%) in Level 2, evaluation or treatment without AD diagnosis; 1,005 (14.5%) in Level 3, a single AD diagnosis (asthma, emphysema/COPD, or recurrent bronchitis); 279 (4.0%) in Level 4, asthma and another AD. By 9/11/2010, the pyramid distribution changed considerably, with Level 1 decreasing to 2,612 (37.7% of the cohort), and Levels 3 (N=1,530) and 4 (N=796) increasing to 22.1% and 11.5% of the cohort, respectively. Symptoms, spirometry measurements and healthcare utilization were associated with higher pyramid levels. Conclusions: Respiratory diagnoses, even four years after a major inhalation event, are not the only drivers of future healthcare utilization. Symptoms and abnormal FEV-1 values must also be considered if clinicians and healthcare administrators are to accurately anticipate future treatment needs, years after initial exposure. Am. J. Ind. Med. 56:870-880, 2013.
机译:背景:本研究利用四级金字塔框架来了解症状报告和/或异常肺功能与气道疾病(AD)诊断之间的关系,其中包括暴露于WTC的消防员的哮喘,复发性支气管炎和COPD /肺气肿。我们比较了两个时间点的金字塔等级分布:到2005年9月11日和到2010年9月11日。方法:我们研究了6,931名WTC接触的FDNY消防员,他们在早期完成了监控检查,并至少进行了两次额外的随访检查9/11 / 2005-9 / 11/2010。结果:到9/11/2005为止,金字塔结构如下:1级为4,039(58.3%),无呼吸评估或治疗;在没有AD诊断的情况下进行2级评估或治疗的患者为1,608(23.2%); 3级,单次AD诊断(哮喘,肺气肿/ COPD或复发性支气管炎)为1,005(14.5%); 4级哮喘患者中有279人(4.0%),另有AD。到2010年9月11日,金字塔分布发生了显着变化,级别1下降到2,612(占同类群的37.7%),级别3(N = 1,530)和4(N = 796)分别增长到22.1%和11.5%队列。症状,肺活量测定和医疗保健利用率与较高的金字塔等级有关。结论:即使在重大吸入事件发生四年后,呼吸系统诊断也不是未来医疗保健利用的唯一驱动力。如果临床医生和医疗保健管理人员要在首次接触后数年准确预测未来的治疗需求,也必须考虑症状和FEV-1异常值。上午。 J.工业医学。 56:870-880,2013。

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