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首页> 外文期刊>Anaesthesia: Journal of the Association of Anaesthetists of Great Britain and Ireland >Near-fatal anaphylaxis caused by human serum albumin in fibrinogen and erythrocyte concentrates
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Near-fatal anaphylaxis caused by human serum albumin in fibrinogen and erythrocyte concentrates

机译：人血清白蛋白在纤维蛋白原和红细胞浓缩物中引起的近致命过敏反应

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摘要

A 40-year-old man developed anaphylactic shock during surgical replacement of a prolapsed mitral valve during general anaesthesia and an attenuated reaction (Grade 2), three days later during a blood transfusion. Human serum albumin, a component of the fibrinogen concentrate used postoperatively with the erythrocyte concentrate, was identified as the trigger, confirmed by positive skin prick and intradermal tests. Any anaphylaxis during the peri-operative period should cause the clinician to perform allergy tests for identification of the culprit drug and, sometimes, culprit additive. Testing of human serum albumin, acting as hidden allergen, should be included, especially where there has been a blood transfusion.
机译：一名40岁的男子在全麻期间三天后在手术置换脱垂的二尖瓣和反应减弱的过程中出现了过敏性休克（2级）。皮肤刺痛和皮内试验阳性证实，人血清白蛋白是术后与红细胞浓缩物一起使用的纤维蛋白原浓缩物的组成部分。围手术期的任何过敏反应都应使临床医生进行过敏测试，以鉴定罪魁祸首药物和有时的罪魁祸首添加剂。应包括对作为隐性过敏原的人血清白蛋白进行检测，尤其是在输血的情况下。

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