The effect of lipid monolayer in-plane rigidity on in vivo microbubble circulation persistence

Sumit Garg; Alex A. Thomas; Mark A. Borden

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The effect of lipid monolayer in-plane rigidity on in vivo microbubble circulation persistence

机译：脂质单层刚度对体内微胶石循环持久性的影响

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Ultrasound (US) medical imaging is safe, inexpensive, portable, and offers excellent spatial resolution and real-time visualization, but its use for advanced diagnostic imaging is hampered by poor soft tissue contrast, which makes the images difficult to interpret. Tissue contrast can be improved by intravascular injection of microbubble ultrasound contrast agents [1], but their short circulation lifetime somewhat limits their broad use in clinical cardiology and radiology. In this study, we overcome this limitation as we significantly prolonged the circulation lifetime of micro-bubbles by making changes in the microbubble lipid shell composition.

机译：超声（美国）医学成像是安全的，便宜的便携式，提供出色的空间分辨率和实时可视化，但其用于高级诊断成像的用途受到较差的软组织对比度，这使得图像难以解释。通过血管内注射微泡超声造影剂的组织对比度可以提高[1]，但它们的短循环寿命有点限制它们在临床心脏病学和放射学的广泛使用。在这项研究中，我们通过在微泡脂壳组合物的变化改变，克服了这种限制。

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《Biomaterials》 |2013年第28期|共9页
作者
Sumit Garg; Alex A. Thomas; Mark A. Borden;
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Department of Mechanical Engineering Materials Science and Engineering Program University of;

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正文语种 eng
中图分类生物医学工程;
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1. The effect of lipid monolayer in-plane rigidity on in vivo microbubble circulation persistence [J] . Sumit Garg, Alex A. Thomas, Mark A. Borden Biomaterials . 2013,第28期

机译：脂质单层刚度对体内微胶石循环持久性的影响
2. Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers [J] . Langeveld Simone A. G., Schwieger Christian, Beekers Ines, Langmuir: The ACS Journal of Surfaces and Colloids . 2020,第12期

机译：磷脂涂覆的微泡和单层中的配体分布和脂质相行使
3. Dissolution behavior of lipid monolayer-coated, air-filled microbubbles: Effect of lipid hydrophobic chain length [J] . Borden MA., Longo ML. Langmuir: The ACS Journal of Surfaces and Colloids . 2002,第24期

机译：脂质单层包被的充气微气泡的溶解行为：脂质疏水链长度的影响
4. Lipids Lay Thyselves Down: Redox-Induced Lipid Vesicle Fusion Onto Ferrocene-Terminated Self-Assembled Monolayers [C] . Ons Hmam, Antonella Badia Meeting of the Electrochemical Society;International Meeting on Chemical Sensors . 2020

机译：脂质将毒品缩小：氧化还原诱导的脂质囊泡融合到二茂茂丙烯封端的自组装单层上
5. The microstructure and dissolution behavior of lipid-monolayer-coated, air-filled microbubble. [D] . Pu, Gang. 2006

机译：脂质单层包裹的充气微泡的微观结构和溶解行为。
6. The effect of lipid monolayer in-plane rigidity on in vivo microbubble circulation persistence [O] . Sumit Garg, Alex A. Thomas, Mark A. Borden -1

机译：脂质单层面内刚度对体内微泡循环持久性的影响
7. The effect of lipid monolayer in-plane rigidity on in vivo microbubble circulation persistence [O] . Sumit Garg, Alex A. Thomas, Mark A. Borden 2013

机译：脂质单层刚度对体内微胶石循环持久性的影响

The effect of lipid monolayer in-plane rigidity on in vivo microbubble circulation persistence

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