Structural characterization of P1′-diversified urea-based inhibitors of glutamate carboxypeptidase II

著录项

• 来源
  《Bioorganic and Medicinal Chemistry Letters》 |2014年第10期|共6页
• 作者

  PavlicekJ.; PtacekJ.; CernyJ.; ByunY.; SkultetyovaL.; PomperM.G.; LubkowskiJ.; BarinkaC.;

  展开▼
• 作者单位

  Institute of Biotechnology Academy of Sciences of the Czech Republic V.v.i. Laboratory of;

  Institute of Biotechnology Academy of Sciences of the Czech Republic V.v.i. Laboratory of;

  Institute of Biotechnology Academy of Sciences of the Czech Republic V.v.i. Laboratory of;

  Russell H. Morgan Department of Radiology and Radiological Science Johns Hopkins Medical;

  Institute of Biotechnology Academy of Sciences of the Czech Republic V.v.i. Laboratory of;

  Russell H. Morgan Department of Radiology and Radiological Science Johns Hopkins Medical;

  Center for Cancer Research Frederick National Laboratory for Cancer Research Macromolecular;

  Institute of Biotechnology Academy of Sciences of the Czech Republic V.v.i. Laboratory of;

  展开▼
• 收录信息
• 原文格式 PDF
• 正文语种 eng
• 中图分类 药学;
• 关键词

  GCPII; Metallopeptidase; Prostate-specific membrane antigen; PSMA; Structure-based drug design; Urea-based inhibitor; X-ray crystallography;

  机译：GCPII;金属肽酶;前列腺特异性膜抗原;PSMA;基于结构的药物设计;基于尿素的抑制剂;X射线晶体学;