Experimentally Induced Mammalian Models of Glaucoma

Makoto Ishikawa; Takeshi Yoshitomi; Charles F. Zorumski; Yukitoshi Izumi

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Experimentally Induced Mammalian Models of Glaucoma

机译：实验诱导哺乳动物的青光眼模型

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A wide variety of animal models have been used to study glaucoma. Although these models provide valuable information about the disease, there is still no ideal model for studying glaucoma due to its complex pathogenesis. Animal models for glaucoma are pivotal for clarifying glaucoma etiology and for developing novel therapeutic strategies to halt disease progression. In this review paper, we summarize some of the major findings obtained in various glaucoma models and examine the strengths and limitations of these models.

机译：各种各样的动物模型已经用于研究青光眼。虽然这些模型提供了有关该疾病的宝贵信息，但由于其复杂的发病机制，仍然没有理想的模型用于研究青光眼。青光眼的动物模型是针对阐明青光眼病因的关键，并用于制定新的治疗策略，以暂停疾病进展。在本文中，我们总结了各种青光眼模型中获得的一些主要发现，并检查了这些模型的优势和局限性。

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《BioMed research international》 |2015年第19期|共1页
作者
Makoto Ishikawa; Takeshi Yoshitomi; Charles F. Zorumski; Yukitoshi Izumi;
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作者单位

Department of Ophthalmology Akita Graduate University School of Medicine;

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正文语种 eng
中图分类基础医学;
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1. Experimentally Induced Mammalian Models of Glaucoma [J] . Makoto Ishikawa, Takeshi Yoshitomi, Charles F. Zorumski, BioMed research international . 2015,第19期

机译：实验诱导哺乳动物的青光眼模型
2. Neuroprotective effect of a dietary supplement against glutamate-induced cytotoxicity in experimental glaucoma models [J] . Kurose Takahiro, Takezawa Tsubasa, Shiratori Shuu, Investigative ophthalmology & visual science . 2017,第8期

机译：膳食补充剂对实验性青光眼模型中谷氨酸诱导的细胞毒性的神经保护作用
3. Characterising the Microbead induced Chronic Experimental Glaucoma (EG) Model using optic coherence tomography (OCT) in non-human primates (NHP) [J] . Chan Anita, Tun Tin Aung, Tun Sai Bo Bo, Investigative ophthalmology & visual science . 2017,第8期

机译：使用光学相干断层扫描（OCT）在非人类灵长类动物（NHP）中的微生物诱导慢性实验青光眼（例如）模型
4. NGF Protect the Retinal Ganglion Cells from Damage Induced by Experimental Glaucoma in Rabbit [C] . Zhirong Lu, Xingliang Cheng, Huaijin Guan, Third International Conference of China on Anatomical Sciences Sep 21-24, 2001 Nantong, China . 2001

机译：NGF保护家兔视网膜神经节细胞免受实验性青光眼所致的伤害
5. Oxidative Stress and Proteomic Studies of Mammalian Models of Age-Related Metabolic Dysfunction in Neurodegenerative Disorders: (1) Upregulation of Pin1 in Alzheimer Mouse Model (2) Analysis of Brain Post-Intranasal Administration of Insulin in Alzheimer and Induced Diabetic Mouse Models (3) Analysis Of Proteome Changes In The Parietal Lobule Of Rhesus Monkey Non-Human Primate Following Resveratrol Supplementation as a Part of a Western-Diet. [D] . Swomley, Aaron Michael. 2017

机译：氧化应激和蛋白质组学研究的神经退行性疾病的年龄相关代谢功能障碍的哺乳动物模型：（1）阿尔茨海默病小鼠模型中Pin1的上调（2）鼻内注射胰岛素对老年性痴呆症小鼠和诱导的糖尿病小鼠模型的分析（3）白藜芦醇补充作为西方饮食的一部分，恒河猴非人类灵长类动物顶叶小叶蛋白质组变化的分析。
6. Experimentally Induced Mammalian Models of Glaucoma [O] . Makoto Ishikawa, Takeshi Yoshitomi, Charles F. Zorumski, -1

机译：实验诱导的青光眼哺乳动物模型
7. Experimentally induced mammalian models of glaucoma [O] . Ishikawa Makoto, Yoshitomi Takeshi, Zorumski Charles F, 2015

机译：实验诱导的青光眼哺乳动物模型
8. Expression and Function of Heat Shock Proteins in the Mammalian Gut During Experimentally Induced Hypoxia and Exogenous Stress [R] . Murashov, A. K. 1999

机译：热休克蛋白在哺乳动物肠道实验性缺氧和外源性应激过程中的表达和功能

Experimentally Induced Mammalian Models of Glaucoma

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