首页> 外文期刊>Bulletin of experimental biology and medicine >Survival and Migration of Rat Olfactory Ensheathing Cells after Transplantation into Posttraumatic Cysts in the Spinal Cord
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Survival and Migration of Rat Olfactory Ensheathing Cells after Transplantation into Posttraumatic Cysts in the Spinal Cord

机译:大鼠嗅鞘细胞移植到脊髓前肠囊肿后的存活率和迁移

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摘要

We studied survival of rat ensheathing cells after transplantation into experimental posttraumatic cysts. These cells were prepared according to our original protocol, labeled with intravital membrane dye PKH26, and transplanted into posttraumatic cysts of the spinal cord. The presence of cysts was verified by magnetic resonance imaging. Olfactory ensheathing cells were detected in the spinal cord by the immunofluorescence method. It was shown that rat olfactory ensheathing cells survived in the spinal cord over 4 weeks and their migration was observed. High survival rate and the possibility of obtaining olfactory ensheathing cells from the olfactory mucosa of patients for creation of an autologous preparation allow considering them as very promising material for the treatment of patients with posttraumatic cysts of the spinal cord.
机译:我们研究了移植到实验后囊肿后大鼠鞘细胞的存活。 这些细胞根据我们的原始方案制备,用腔内膜染料PKH 26标记,并移植到脊髓的错误后囊肿中。 通过磁共振成像验证囊肿的存在。 通过免疫荧光法在脊髓中检测嗅鞘细胞。 结果表明,大鼠嗅鞘细胞在4周超过4周的脊髓中存活,并且观察到它们的迁移。 高存活率和从患者的嗅鞘中获得嗅鞘细胞的可能性,以创造自体制备,允许他们认为它们是治疗脊髓肠道囊肿患者的非常有希望的材料。

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