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首页> 外文期刊>ACS applied materials & interfaces >Antimicrobial Copper-Based Materials and Coatings: Potential Multifaceted Biomedical Applications
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Antimicrobial Copper-Based Materials and Coatings: Potential Multifaceted Biomedical Applications

机译：抗微生物铜基材料和涂层：潜在的多方面生物医学应用

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摘要

Surface contamination by microbes leads to several detrimental consequences like hospital- and device-associated infections. One measure to inhibit surface contamination is to confer the surfaces with antimicrobial properties. Copper's antimicrobial properties have been known since ancient times, and the recent resurgence in exploiting copper for application as antimicrobial materials or coatings is motivated by the growing concern about antibiotic resistance and the pressure to reduce antibiotic use. Copper, unlike silver, demonstrates rapid and high microbicidal efficacy against pathogens that are in close contact under ambient indoor conditions, which enhances its range of applicability. This review highlights the mechanisms behind copper's potent antimicrobial property, the design and fabrication of different copper-based antimicrobial materials and coatings comprising metallic copper/copper alloys, copper nanoparticles or ions, and their potential for practical applications. Finally, as the antimicrobial coatings market is expected to grow, we offer our perspectives on the implications of increased copper release into the environment and the potential ecotoxicity effects and possibility of development of resistant genes in pathogens.
机译：微生物的表面污染导致医院和设备相关的感染等几种不利后果。抑制表面污染的一种措施是用抗微生物性质赋予表面。铜的抗微生物性质已知以自古以来已知，并且最近利用铜应用于抗微生物材料或涂层的抗性的复兴是由于对抗生素抗性和降低抗生素使用的压力而越来越多的贡献。与银不同的铜证明了在环境室内条件下紧密接触的病原体的快速和高染色效果，这提高了其适用范围。本综述突出了铜有效抗菌性的机制，不同铜基抗微生物材料的设计和制造以及包含金属铜/铜合金，铜纳米粒子或离子的涂层及其对实际应用的潜力。最后，随着预期抗微生物涂料市场的增加，我们提供了对增加铜释放到环境的影响以及潜在的生态毒性效应以及在病原体中抗性基因的可能性的观点。

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