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首页> 外文期刊>Applied radiation and isotopes: including data, instrumentation and methods for use in agriculture, industry and medicine >Determination of boron concentration in blood and tissue samples from patients with liver metastases of colorectal carcinoma using Prompt Gamma Ray Activation Analysis (PGAA).
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Determination of boron concentration in blood and tissue samples from patients with liver metastases of colorectal carcinoma using Prompt Gamma Ray Activation Analysis (PGAA).

机译:促进γ射线激活分析(PGAA)肝转移患者血液和组织样品中硼浓度的测定。

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摘要

As part of the studies on Boron Neutron Capture Therapy at the University of Mainz, Germany, a clinical trial has been started in which, four patients suffering from liver metastases of colorectal carcinoma have been enrolled. Specimens of blood and healthy tissue samples taken from the patients were measured at the PGAA facilities at the HFR in Petten, The Netherlands, and at the FRM II in Munich, Germany. From the measured boron concentrations, pharmacokinetic curves and blood-to-tissue concentration ratios were produced.
机译:作为德国华美州大学硼中子捕获疗法研究的一部分,已经开始临床试验,其中患有患有结直肠癌肝脏转移的患者已经注册。 从患者,荷兰,荷兰的HFR的PGAA设施中测量患者的血液和健康组织样品标本,并在德国慕尼黑的FRM II。 从测得的硼浓度,产生药代动力学曲线和血对组织浓度比。

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