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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >A Disease-specific Score for Estimating Survival After Irradiation of Bone Metastases from Colorectal Cancer
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A Disease-specific Score for Estimating Survival After Irradiation of Bone Metastases from Colorectal Cancer

机译：一种疾病特异性分数，用于估算成直肠癌骨转移辐射后的存活

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Background/Aim: Estimating survival is important for treatment personalization in patients with metastatic cancer. In this study, we aimed to develop a survival score for patients irradiated for bone metastases from colorectal cancer. Patients and Methods: Eleven factors were retrospectively analyzed in 25 patients, including age, gender, Eastern Cooperative Oncology Group performance score, tumor site, time between diagnosis of colorectal cancer and irradiation, visceral or other bone metastases, type and number of irradiated sites, upfront surgery and previous systemic treatment. Results: On multivariate analysis, performance score (p=0.005) and previous systemic treatment (p=0.007) were significantly associated with survival and used for the score. One point (performance score 0-1 or no previous systemic treatment) or 0 points (performance score >= 2 or previous systemic treatment) were assigned resulting in 0, 1 or 2 points. Six-month survival rates of these groups were 0%, 64% and 100%, respectively. Conclusion: This new survival score can support physicians during personalization of treatment for patients with bone metastases from colorectal cancer.
机译：背景/目的：估算存活对于转移性癌症患者的个性化是重要的。在这项研究中，我们旨在为从结肠直肠癌照射骨转移的患者发育生存率。患者和方法：在25名患者中回顾性分析了11个因素，包括年龄，性别，东方合作肿瘤组成绩，肿瘤部位，诊断结直肠癌和辐射，内脏或其他骨转移，辐照场地的类型和数量，前期手术和以前的全身治疗。结果：关于多变量分析，性能评分（P = 0.005）和先前的全身治疗（P = 0.007）与生存显着相关，并用于得分。指定了一个点（性能分数0-1或以前的全身治疗）或0分（性能评分> = 2或先前的全身治疗），导致0,1或2点。这些群体的六个月存活率分别为0％，64％和100％。结论：这种新的存活评分可以在患有结肠直肠癌骨转移患者的治疗过程中支持医生。

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