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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Characteristics of Five-year Survivors After Liver Resection for Colorectal Liver Metastases in Modern Chemotherapy
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Characteristics of Five-year Survivors After Liver Resection for Colorectal Liver Metastases in Modern Chemotherapy

机译:现代化疗中肝切除肝切除肝切除术后五年幸存者的特征

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Background/Aim: The aim of this study was to evaluate whether modern chemotherapy has changed characteristics of actual five- year survivors after liver resection for colorectal liver metastasis ( CRLM). Patients and Methods: The records of 210 patients, who underwent curative liver resection for CRLM at our institution between January 1990 and May 2014, were reviewed. The patients treated before 2004 when modern chemotherapy was not introduced were compared with the patients treated after 2005. Results: Actual five-year survivor rates were significantly higher after 2005 (33.3% vs. 49.0%, p=0.022). Preoperative characteristics of actual five-year survivors were not different. The median survival time after non-resectable recurrence was significantly longer after 2005 (20.3 vs. 8.7 months, p=0.002). The proportion of 5-year survivors with recurrent site was significantly higher after 2005 (34.0% vs. 10.5%, p=0.019). Conclusion: Actual fiveyear survivors have increased by modern chemotherapy. However, approximately one-third of them were not cured.
机译:背景/目的:本研究的目的是评估现代化疗是否在肝脏切除肝转移(CRLM)肝切除后改变了实际的五年幸存者的特征。患者和方法:210例患者的记录,在1990年1月至2014年5月在我们的机构接受了CRLM治疗肝切除的患者。与2005年后未介绍的患者进行比较2004年之前治疗的患者。结果:2005年后,实际的五年幸存者率明显高出明显高(33.3%vs.49.0%,P = 0.022)。实际五年幸存者的术前特征没有不同。在2005年后不可切除复发后的中位存活时间明显更长(20.3节,8.7个月,P = 0.002)。 2005年后,5年幸存者的比例明显高(34.0%vs.10.5%,P = 0.019)。结论:现代化化疗的实际五年浆幸存者增加。然而,大约三分之一的人没有治愈。

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