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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >A Simple Clinical Instrument to Predict the Survival Probability of Breast Cancer Patients Receiving Radiotherapy for Bone Metastases
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A Simple Clinical Instrument to Predict the Survival Probability of Breast Cancer Patients Receiving Radiotherapy for Bone Metastases

机译：一种简单的临床仪器，以预测接受骨转移放射治疗的乳腺癌患者的存活概率

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Background/Aim: Individualization of treatment may improve the outcome of patients with bone metastases from breast cancer. To support physicians when selecting individualized programs for these patients, a simple instrument for predicting survival was created. Patients and Methods: In 126 female patients with breast cancer irradiated for bone metastases, 11 characteristics were evaluated with respect to survival. Results: On Cox regression analysis, Eastern Cooperative Oncology Group performance score (01 vs. >= 2; p=0.032) and visceral metastases (absence vs. presence; p=0.017) were independently associated with survival and incorporated into the scoring instrument. Three prognostic groups (0, 1 or 2 points) were designated with 12-month survival rates of 38%, 57% and 91%, and 24-month survival rates of 32%, 36% and 80%, respectively (p<0.001). Conclusion: This easy-to-use scoring instrument allows physicians to estimate the lifespan of patients irradiated for bone metastases from breast cancer and can facilitate individualization of their treatment.
机译：背景/目的：治疗的个体化可以改善来自乳腺癌的骨转移患者的结果。为了支持医生在为这些患者选择个性化计划时，创建了一种预测生存的简单仪器。患者及方法：在126例女性乳腺癌患者中照射骨转移，相对于存活评估了11种特征。结果：关于Cox回归分析，东方合作肿瘤学群体性能评分（01 vs.> = 2; p = 0.032）和内脏转移（不存在与存在; p = 0.017）与存活相关并掺入评分仪器中。三个预后组（0,1或2个点）以12个月的生存率为38％，57％和91％，24个月存活率分别为32％，36％和80％（P <0.001 ）。结论：这种易于使用的评分仪器允许医生估计来自乳腺癌的骨转移患者的患者的寿命，可以促进其治疗的个体化。

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