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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Clinical Impact of Histological Heterogeneity in the Metastatic Lymph Nodes of Patients with Colorectal Cancer
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Clinical Impact of Histological Heterogeneity in the Metastatic Lymph Nodes of Patients with Colorectal Cancer

机译：结直肠癌患者转移性淋巴结中组织学异质性的临床影响

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Aim: The purpose of this study was to evaluate the clinical impact of histological heterogeneity in patients with node-positive colorectal cancer (CRC). Patients and Methods: One hundred and twenty-nine patients who underwent curative surgical resection for histological node-positive CRC were enrolled. Patients were divided according to the histological heterogeneity in the primary lesion into p-hetero and p-homo groups. The p-hetero group was further divided according to histological heterogeneity in the metastatic lymph nodes into n-hetero and n-homo groups. Results: There were no significant differences between p-homo and p-hetero groups and between n-homo and n-hetero groups in prognosis. However, the recurrence free survival rate of the n-homo group was significantly lower than that of the n-hetero group in the N2 category. Conclusion: Histological heterogeneity in metastatic lymph nodes may be useful for predicting prognosis, and prognosis in those with histological heterogeneity in a metastatic lymph node is not necessarily poor, even in those of the N2 category.
机译：目的：本研究的目的是评估细胞阳性结直肠癌（CRC）患者组织学异质性的临床影响。患者和方法：招募了一百二十九个接受组织学节点阳性CRC治疗手术切除的患者。将患者根据初级病变中的组织学异质性分成p-杂和p-homo基团。根据转移性淋巴结中的组织学异质性进一步分割p-杂组，进入N-杂和N-HOMO基团。结果：P-HOMO和P-杂菌群与N-HOMO和N-杂核基团之间没有显着差异。然而，N-HOMO基团的复发自由存活率显着低于N2类别中的N-杂组。结论：转移性淋巴结中的组织学异质性可用于预测预后，转移淋巴结中具有组织学异质性的预后，即使在N2类别的那些中也不一定差。

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