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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Patterns of Recurrence After Salvage Radiotherapy Encompassing Pelvic Lymphatics in Men with High-risk Prostate Cancer
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Patterns of Recurrence After Salvage Radiotherapy Encompassing Pelvic Lymphatics in Men with High-risk Prostate Cancer

机译：在高危前列腺癌的男性中包含骨盆淋巴管的抢购放疗后复发的复发模式

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Background/Aim: The efficacy of adjuvant or salvage radiation to the regional lymph node area has not been fully investigated in high-risk prostate cancer patients; instead, radiotherapy is limited to the prostate fossa. The present study aimed to assess patterns of recurrence in prostate cancer patients with biochemical failure (BCF) who were treated with whole-pelvic salvage radiotherapy (SRT) following radical prostatectomy. Patients and Methods: The clinical data from 196 high-risk prostate cancer patients who received SRT for BCF after radical prostatectomy were reviewed. BCF after SRT was detected in 80 patients, and 59 patients underwent imaging studies. Results: Twenty four recurrences in 16 patients were identified, including 13 bone metastases, 6 vesicourethral anastomosis site recurrences, and 5 lymph node recurrences (one simultaneous with vesicourethral anastomosis). Regarding the treatment field, no in-field nodal recurrence was observed, whereas 4 out-of-field and 1 edge-of-field recurrences were detected. Conclusion: Locoregional recurrence was most common at the anastomosis site. Most nodal recurrences were located outside the pelvis, suggesting that elective pelvic nodal irradiation should be recommended in a selected patient population.
机译：背景/目的：在高风险前列腺癌患者中尚未全面调查辅助或拯救辐射对区域淋巴结区域的疗效;相反，放射疗法仅限于前列腺窝。本研究旨在评估前列腺癌患者的转发癌症患者的复发模式（BCF），其在自由基前列腺切除术后伴有全盆腔救出放疗（SRT）治疗。患者及方法：综述了自由基前列腺切除术后接受BCF的SRT的196次高风险前列腺癌患者的临床资料。在80名患者中检测到SRT后BCF，59名患者接受了成像研究。结果：鉴定了24例患者的二十四次复发，包括13个骨转移，6个骨转移术，6种膀胱吻合术，5例淋巴结复发（一种同时与vesicourethral吻合术）。关于治疗领域，未观察到局部结节复发，而检测到4个外场和1个现场复发。结论：在吻合遗址患者中最常见的招生复发。大多数节点复发位于骨盆外，建议应在选定的患者人群中建议选择盆腔节点辐照。

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