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首页> 外文期刊>Biotechnology Progress >Prebiotic peptides, their formation, fermentation in the gut, and health implications
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Prebiotic peptides, their formation, fermentation in the gut, and health implications

机译：益生元肽，它们的形成，肠道中发酵，以及健康影响

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Prebiotics can be synthesized from sources other than dietary fibers, such as proteins. The proteins, when processed into peptides have healthful or deleterious effects on the host. Outside living systems, prebiotic peptides (PP) are formed via preformation of amino acids or related monomeric building blocks, resulting in nonenzymatic polymerization/ligation to produce peptides. Whereas, inside living systems like the human gut, many metabolic pathways are involved in PP production, and mostly involve host-microbiota interactions. The interplay is responsible for PP activities and their implications on host amino acid balance and metabolism. Similar to carbohydrates fermentation, PP will yield short chain fatty acids (SCFA), but also branched chain fatty acids (BCFAs), phenols, indole, hydrogen sulfide, amines, and ammonia, capable of biologically mediating molecular signals. This holistic review considers a brief description of prebiotics, and tracks down prebiotic peptides formation processes, interactions with gut microbes, and health outcomes.
机译：益生元可以从膳食纤维（例如蛋白质）以外的来源合成。当加工成肽时，蛋白质对宿主具有健康或有害的影响。在外部生活系统，通过氨基酸或相关单体构建块的预成形形成益生元肽（PP），导致非酶聚合/结扎产生肽。然而，在人体肠道这样的生活系统中，许多代谢途径都参与了PP产量，并且大多涉及宿主微生物脂蛋白相互作用。相互作用负责PP活性及其对宿主氨基酸平衡和新陈代谢的影响。与碳水化合物发酵相似，PP将产生短链脂肪酸（SCFA），而且还产生支链脂肪酸（BCFA），酚，吲哚，硫化氢，胺和氨，能够生物介导的分子信号。该整体综述考虑了益生元的简要描述，并追踪益生元肽形成过程，与肠道微生物的相互作用和健康结果。

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