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首页> 外文期刊>Canadian Veterinary Journal: La Revue Veterinaire Canadienne. >Evaluation of long-acting oxytetracycline and a commercial monovalent vaccine for the control of Campylobacter fetus subsp. venerealis infection in beef bulls
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Evaluation of long-acting oxytetracycline and a commercial monovalent vaccine for the control of Campylobacter fetus subsp. venerealis infection in beef bulls

机译:长效氧化素和商业单价疫苗的评价,用于控制振动杆菌胎儿。 牛肉公牛的Venerealis感染

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摘要

A blinded randomized controlled trial was used to evaluate a multi-modal therapeutic regime for treatment of beef bulls infected with Campylobacter fetus subsp. venerealis (Cfv). Treatment included 2 doses of a commercially available monovalent vaccine and long-acting oxytetracycline applied twice at a 2-week interval with treatment completed 2 weeks before post-treatment observation. Fifteen confirmed Cfv infected bulls were randomly allocated to control (n = 8) or treatment groups {n = 7). Preputial scrapings were collected each week from before infection to 11 weeks following the last treatment. When the polymerase chain reaction (PCR) results for both culture and preputial scrapings were interpreted in parallel, there were no significant differences between treated and untreated bulls. Regardless of the type of diagnostic testing considered, treatment with 2 label doses of this regime did not stop shedding of Cfv in all treated bulls and is, therefore, not recommended as an effective management strategy.
机译:采用一项盲法随机对照试验,对感染弯曲杆菌胎儿亚种的肉牛的多模式治疗方案进行了评估。性病(Cfv)。治疗包括2剂市售单价疫苗和长效土霉素,间隔2周两次,治疗在治疗后观察前2周完成。15头确诊感染Cfv的公牛被随机分配到对照组(n=8)或治疗组{n=7)。从感染前到最后一次治疗后11周,每周收集包皮刮屑。当聚合酶链反应(PCR)检测到结果对于培养物和包皮刮片进行平行解释,治疗和未治疗公牛之间没有显著差异。无论所考虑的诊断试验类型如何,使用2个标记剂量的该方案治疗并不能阻止所有治疗公牛的Cfv脱落,因此,不建议将其作为有效的管理策略。

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    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 动物医学(兽医学);
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