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首页> 外文期刊>Canadian Veterinary Journal: La Revue Veterinaire Canadienne. >Evaluation of long-acting oxytetracycline and a commercial monovalent vaccine for the control of Campylobacter fetus subsp. venerealis infection in beef bulls
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Evaluation of long-acting oxytetracycline and a commercial monovalent vaccine for the control of Campylobacter fetus subsp. venerealis infection in beef bulls

机译：评价长效氧化素和商业单价疫苗进行控制，用于控制胎儿胎儿。 牛肉公牛的Venerealis感染

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摘要

A blinded randomized controlled trial was used to evaluate a multi-modal therapeutic regime for treatment of beef bulls infected with Campylobacter fetus subsp. venerealis (Cfv). Treatment included 2 doses of a commercially available monovalent vaccine and long-acting oxytetracycline applied twice at a 2-week interval with treatment completed 2 weeks before post-treatment observation. Fifteen confirmed Cfv infected bulls were randomly allocated to control (n = 8) or treatment groups {n = 7). Preputial scrapings were collected each week from before infection to 11 weeks following the last treatment. When the polymerase chain reaction (PCR) results for both culture and preputial scrapings were interpreted in parallel, there were no significant differences between treated and untreated bulls. Regardless of the type of diagnostic testing considered, treatment with 2 label doses of this regime did not stop shedding of Cfv in all treated bulls and is, therefore, not recommended as an effective management strategy.
机译：盲化随机对照试验用于评估一种多模态治疗方案，用于治疗患有弯曲杆菌患者感染的牛肉公牛。 Venerealis（CFV）。治疗包括2剂量的商业上可获得的一价疫苗和长效氧杂环素，在治疗后2周完成2周的时间间隔施用两次。将十五条确认的CFV受感染的公牛随机分配给控制（n = 8）或治疗组{n = 7）。每周收集预先收集的刮擦，然后从最后一次治疗后11周收集到11周。当平行解释培养和预扫描的聚合酶链反应（PCR）结果时，治疗和未经治疗的公牛之间没有显着差异。无论考虑的诊断测试的类型如何，用2个标签剂量的治疗程序都没有停止在所有处理的公牛中停止CFV，因此，不建议是有效的管理策略。

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    Nathan E.N. Erickson; Emily Lanigan; Taryn Waugh; Karen Gesy; Cheryl Waldner;

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    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

    Department of Large Animal Clinical Sciences Western College of Veterinary Medicine 52 Campus Drive Saskatoon Saskatchewan S7N 5B4;

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  • 正文语种 eng
  • 中图分类 动物医学（兽医学）;
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