Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route

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• 来源
  《Journal of Medicinal Chemistry》 |2021年第10期|共22页
• 作者

  Vyskocil Stepan; Cardin David; Ciavarri Jeffrey; Conlon Joe; Cullis Courtney; England Dylan; Gershman Rachel; Gigstad Kenneth; Gipson Krista; Gould Alexandra; Greenspan Paul; Griffin Robert; Gulavita Nanda; Harrison Sean; Hu Zhigen; Hu Yongbo; Hata Akito; Huang Jian; Huang Shih-Chung; Janowick Dave; Jones Matthew; Kolev Vihren; Langston Steven P.; Lee Hong Myung; Li Gang; Lok David; Ma Liting; Mai Doanh; Malley Jenna; Matsuda Atsushi; Mizutani Hirotake; Mizutani Miho; Molchanova Nina; Nunes Elise; Pusalkar Sandeep; Renou Christelle; Rowland Scott; Sato Yosuke; Shaw Michael; Shen Luhua; Shi Zhan; Skene Robert; Soucy Francois; Stroud Steve; Xu He; Xu Tianlin; Abu-Yousif Adnan O.; Zhang Ji;

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• 作者单位

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co DMPK Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Global Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Global Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co DMPK Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Immunooncol Biol Cambridge MA 02139 USA;

  Takeda Pharmaceut Int Co Drug Discovery Sci Cambridge MA 02139 USA;

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• 原文格式 PDF
• 正文语种 eng
• 中图分类 药学;
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