Using ProteomeScout: A Resource of Post-Translational Modifications, Their Experiments, and the Proteins That They Annotate

Arshag D. Mooradian; Jason M. Held; Kristen M. Naegle

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Using ProteomeScout: A Resource of Post-Translational Modifications, Their Experiments, and the Proteins That They Annotate

机译：使用proteomescout：翻译后修饰的资源，他们的实验和它们注释的蛋白质

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摘要

Post-translational modifications (PTMs) of protein amino acids are ubiquitous and important to protein function, localization, degradation, and more. In recent years, there has been an explosion in the discovery of PTMs as a result of improvements inPTM measurement techniques, including quantitative measurements of PTMs across multiple conditions. ProteomeScout is a repository for such discovery and quantitative experiments and provides tools for visualizing PTMs within proteins, including where they are relative to other PTMS, domains, mutations, and structure. ProteomeScout additionally provides analysis tools for identifying statistically significant relationships in experimental datasets. This unit describes four basic protocols for working with the Pro-teomeScout Web interface or programmatically with the database download.

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来源
《Current Protocols in Bioinformatics》 |2017年第59期|共27页
作者
Arshag D. Mooradian; Jason M. Held; Kristen M. Naegle;
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作者单位

Department of Medicine Division of Hematology and Oncology Washington UniversitySchool of Medicine in St. Louis St. Louis Missouri;

Department of Anesthesiology Washington University School of Medicine in St. Louis St. Louis Missouri;

Department of Biomedical Engineering and Center for Biological Systems Engineering Washington University in St. Louis St. Louis Missouri;

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原文格式 PDF
正文语种 eng
中图分类遗传学;
关键词
compendia; dataset analysis; post-translational modifications; protein annotations; protein visualization;

机译：Comendia;数据集分析;翻译后修饰;蛋白质注释;蛋白质可视化;

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机译：单元13.32使用Proteomesceut：翻译后修饰的资源，他们的实验和它们注释的蛋白质
6. Using ProteomeScout: A Resource of Post-Translational Modifications, Their Experiments, and the Proteins That They Annotate [J] . Arshag D. Mooradian, Jason M. Held, Kristen M. Naegle Current Protocols in Bioinformatics . 2017,第Suppla59期

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机译：ProteomeScout：用于翻译后修饰和蛋白质的存储库和分析资源
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机译：古细菌中的蛋白质糖基化：后转化修饰以增强极端蛋白质稳定性

Using ProteomeScout: A Resource of Post-Translational Modifications, Their Experiments, and the Proteins That They Annotate

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