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Construction of Ultralarge Two-Dimensional Fluorescent Protein Arrays via a Reengineered Rhodamine B-Based Molecular Tool

机译:通过再生罗丹明B基分子工具构建UltraRarge二维荧光蛋白阵列

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摘要

The self-luminous property of enhanced green fluorescent protein (EGFP) makes it an extremely attractive building block for creating functional biomaterials. A practical challenge in the design of EGFP-based materials, however, stems from the structural and chemical heterogeneity of the EGFP surface. In this study, a maleimide-functionalized rhodamine B molecule (RhG_(2)M) was designed as a versatile molecular tool to overcome this obstacle. Site-specific modification of an EGFP variant (EGFP-4C) with RhG_(2)M allowed for the fabrication of a series of well-defined two-dimensional (2D) arrays that span nano- and micrometer scales. Furthermore, the resulting ultralarge 2D EGFP-4C arrays feature both structural uniformity and flexibility, together with the inherent optical properties, making them advanced materials with great potential for practical applications. In addition, this strategy can be further extended into three dimensions and applied to the modular generation of periodic functional materials with more complex structures.
机译:None

著录项

  • 来源
    《ACS Macro Letters》 |2021年第2期|共5页
  • 作者单位

    College of Material Chemistry and Chemical Engineering Hangzhou Normal University;

    State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University;

    State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University;

    College of Material Chemistry and Chemical Engineering Hangzhou Normal University;

    State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University;

    State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University;

    State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University;

    State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University;

    College of Material Chemistry and Chemical Engineering Hangzhou Normal University;

    College of Material Chemistry and Chemical Engineering Hangzhou Normal University;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 有机化学;
  • 关键词

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