Antipsychotics and hemodialysis: A systematic review

Sutar Roshan; Atlani Mahendra Kumar; Chaudhary Pooja

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Antipsychotics and hemodialysis: A systematic review

机译：抗精神病药和血液透析：系统评价

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Objective: Antipsychotics play a crucial role in the management of behavioral problems in patients undergoing hemodialysis. Oral and injectable antipsychotics are routinely prescribed to control emergent delirium or exacerbation of previous psychiatric symptoms. However scanty literature is available on the pharmacokinetics of antipsychotics in such patients. Avoiding amisulpride and warning against increasing the dosage in renal failure is the only recommendation by drug manufacturers and clinical guidelines. Hemodialysis affects the volume of distribution (V-d) and blood levels of antipsychotics in a complex manner. It is hence difficult to equate data on renal failure with hemodialysis to reliably predict the treatment response.

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来源
《Asian journal of psychiatry》 |2021年第1期|共9页
作者
Sutar Roshan; Atlani Mahendra Kumar; Chaudhary Pooja;
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作者单位

All India Inst Med Sci AIIMS Dept Psychiat Bhopal India;

All India Inst Med Sci AIIMS Dept Nephrol Bhopal India;

All India Inst Med Sci AIIMS Dept Psychiat Bhopal India;

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原文格式 PDF
正文语种 eng
中图分类神经病学与精神病学;
关键词
Antipsychotic; Hemodialysis; Adverse effects; Pharmacokinetics; Renal failure;

机译：抗精神病药;血液透析;不良反应;药代动力学;肾功能衰竭;

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Antipsychotics and hemodialysis: A systematic review

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