Cetirizine: dystonia and other extrapyramidal disorders

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Cetirizine: dystonia and other extrapyramidal disorders

机译：甲嘧啶：Dystonia和其他外锥形疾病

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Dystonia has been observed with cetirizine, a histamine H1-receptor antagonist, particularly in young children. The outcome was most often favourable after the drug was discontinued. A similar risk can be expected with levoceti-rizine, whereas the risk seems lower with lorata-dine and desloratadine. In practice, cetirizine and loratadine are the first-choice antihistamines. However, given their very real adverse effects, their use should not be trivi-alised, and care must be taken to avoid overdose and to limit the duration of use.

机译：用组胺H1受体拮抗剂西替利嗪观察到肌张力障碍，尤其是在幼儿中。停药后，结果往往是有利的。左旋西替利嗪也有类似的风险，而氯雷他定和地氯雷他定的风险似乎更低。实际上，西替利嗪和氯雷他定是首选抗组胺药。然而，考虑到它们真正的副作用，它们的使用不应该被三化，必须注意避免过量，并限制使用时间。

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《Prescrire international》 |2020年第219期|共2页
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中图分类药学;
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Cetirizine: dystonia and other extrapyramidal disorders

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