The ups and downs of drug discovery: the early history of Fidaxomicin

McAlpine James B.

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The ups and downs of drug discovery: the early history of Fidaxomicin

机译：药物发现的起伏：Fidaxomicin的早期历史

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The path from antibiotic compound discovery to the market is marked by many potholes and its negotiation is often dependent on luck and persistence. Perhaps the prime example of this is the case of the development of tiacumicin B to Fidaxomicin, where both parameters were critical and the path was particularly circuitous.

机译：从抗生素化合物的发现到市场的道路上有许多凹坑，谈判往往取决于运气和毅力。也许这方面的主要例子是将硫库米星B发展为非达西霉素的情况，这两个参数都很关键，而且路径特别迂回。

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《The Journal of Antibiotics: An International Journal》 |2017年第5期|共3页
作者
McAlpine James B.;
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作者单位

Univ Illinois Coll Pharm Dept Med Chem &

Pharmacognosy 833 South Wood St Chicago IL 60612 USA;

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原文格式 PDF
正文语种 eng
中图分类药学;
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4. The ups and downs of drug discovery: the early history of Fidaxomicin [J] . McAlpine James B. The Journal of Antibiotics: An International Journal . 2017,第5期

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The ups and downs of drug discovery: the early history of Fidaxomicin

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