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Is Aging Biology Ageist?

机译:衰老生物学阶级主义者吗?

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摘要

The scientific questions we pursue are shaped by our cultural assumptions and biases, often in ways we are unaware. Here, we argue that modern biases against older adults (ageism) have unconsciously led aging biologists to assume that traits of older individuals are negative and those of younger individuals positive. We illustrate this bias with the example of how a medieval Chinese scholar might have approached the task of understanding aging biology. In particular, aging biologists have tended to emphasize functional declines during aging, rather than biological adaptation and population selection or composition processes; the reality is certainly that all these processes interact. Failure to make these distinctions could lead to interventions that improve superficial markers of aging while harming underlying health, particularly as the health priorities of older adults (autonomy, function, freedom from suffering, etc.) are often quite different from the goals of aging biologists (reducing disease, prolonging life). One approach to disentangling positive, negative, and neutral changes is to map trajectories of change across the life course of an individual (physiobiography). We emphasize that our goal is not to criticize our colleagues-we have been guilty too-but rather to help us all improve our science.
机译:我们追求的科学问题是由我们的文化假设和偏见决定的,通常是以我们不知道的方式。在这里,我们认为现代人对老年人的偏见(老年歧视)不知不觉地导致老年生物学家认为老年人的特征是消极的,而年轻人的特征是积极的。我们用一个中世纪中国学者如何理解衰老生物学的例子来说明这种偏见。尤其是,老龄化生物学家倾向于强调老龄化过程中的功能衰退,而不是生物适应和种群选择或组成过程;事实上,所有这些过程都是相互作用的。不进行这些区分可能会导致干预措施改善老化的表面标志,同时损害基本健康,尤其是因为老年人的健康优先事项(自主性、功能、免受痛苦等)往往与衰老生物学家的目标(减少疾病、延长寿命)大不相同。解开积极、消极和中性变化的一种方法是绘制个体生命过程中的变化轨迹(生理传记)。我们强调,我们的目标不是批评我们的同事——我们也有罪——而是帮助我们所有人改进我们的科学。

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