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首页> 外文期刊>Annals of thoracic and cardiovascular surgery: official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia >Solitary fibrous tumor of the thymus with local invasiveness and pleural dissemination: report of a case.
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Solitary fibrous tumor of the thymus with local invasiveness and pleural dissemination: report of a case.

机译：胸腺的局部纤维性肿瘤伴局部浸润和胸膜播散：一例报告。

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摘要

A 74-year-old asymptomatic female presented with an anterior mediastinal mass incidentally discovered on a routine chest X-ray. Systemic evaluation demonstrated no metastatic lesions. The patient underwent an extended thymectomy via median sternotomy on suspicion of a thymoma. The tumor had arisen from the left half of the thymus without a pedicle and had directly invaded into the left lung and pericardium. The tumor was resected with the entire thymic tissue, and the invaded lung and pericardium were resected en-bloc. The size of the tumor was 5.3x4.0 cm. A disseminated lesion on the mediastinal pleura was also resected. Histopathologically, the lesion mainly consisted of non-atypical spindle-shaped tumor cells in a so-called "patternless pattern" with various densities of collagenous background. Pleomorphism and mitoses were not significant. Immunohistochemical analysis revealed mesenchymal positive markers such as vimentin and CD34. Epithelial markers such as CAM 5.2 and AE1/AE3 were negative. S-100protein and desmin were not stained. Solitary fibrous tumor of the thymus was diagnosed histologically. Postoperative adjuvant chemotherapy or radiotherapy was not undertaken because the benefits were uncertain. She is well without recurrence 3 months after the operation.
机译：一名74岁无症状的女性在常规胸部X光检查中偶然发现了前纵隔肿块。系统评价未见转移灶。由于怀疑胸腺瘤，患者通过正中胸骨切开术进行了扩大的胸腺切除术。肿瘤起源于胸腺的左半部分，无蒂，并直接侵入左肺和心包。切除了整个胸腺组织的肿瘤，并整体切除了侵袭的肺和心包。肿瘤的大小为5.3x4.0cm。还切除了纵隔胸膜上的一个弥散性病变。在组织病理学上，病变主要由非典型纺锤形肿瘤细胞组成，呈所谓的“无模式”，具有各种密度的胶原蛋白背景。多态性和有丝分裂不显着。免疫组织化学分析显示间质阳性标志物，例如波形蛋白和CD34。上皮标志物，例如CAM 5.2和AE1 / AE3为阴性。 S-100蛋白和结蛋白未染色。通过组织学诊断为胸腺的孤立性纤维性肿瘤。由于获益不确定，因此未进行术后辅助化疗或放疗。术后三个月无复发。

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