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首页> 外文期刊>Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology >Paroxysmal dysarthria-ataxia syndrome: Literature review on MRI findings and report of a peculiar case with clinically isolated syndrome coexisting with anti-N-methyl-D-aspartate receptor antibodies
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Paroxysmal dysarthria-ataxia syndrome: Literature review on MRI findings and report of a peculiar case with clinically isolated syndrome coexisting with anti-N-methyl-D-aspartate receptor antibodies

机译：阵发性缺陷症 - Ataxia综合征：关于MRI调查结果的文献综述和临床上综合征与抗N-甲基-D-天冬氨酸受体抗体共存的特殊案例的报告

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摘要

Paroxysmal dysarthria and ataxia (PDA) syndrome constitutes a rare neurological disorder, and is generally reported in cases of multiple sclerosis (MS) involving the midbrain. We present an illustrative case of 32-year-old female who developed clinically isolated syndrome manifested paroxysmal dysarthria, ataxia, ptosis and diplopia, coexisting with anti-N-methyl-D-aspartate receptor antibodies. We review the literature and identify 23 other cases with brain MRI examinations to summarize the lesion locations and clinical characteristics of PDA syndrome, and ultimately provide a new framework for understanding this rare condition.
机译：阵发性构音障碍和共济失调（PDA）综合征是一种罕见的神经系统疾病，通常在涉及中脑的多发性硬化（MS）病例中报告。我们报告一例32岁女性患者，其临床孤立综合征表现为阵发性构音障碍、共济失调、上睑下垂和复视，并伴有抗N-甲基-D-天冬氨酸受体抗体。我们回顾了文献，并通过脑MRI检查确定了23例其他病例，以总结PDA综合征的病变部位和临床特征，并最终为理解这一罕见疾病提供了一个新的框架。

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