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首页> 外文期刊>Journal of stroke and cerebrovascular diseases: The official journal of National Stroke Association >Red and White Thrombus Characteristics in Patients Undergoing Carotid Endarterectomy
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Red and White Thrombus Characteristics in Patients Undergoing Carotid Endarterectomy

机译：颈动脉胚胎切除术患者的红色和白色血栓特征

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摘要

Objective: The study aimed to compare the characteristics of red and white thrombi in patients undergoing carotid endarterectomy. Material and Methods: The study was conducted in 81 patients with ischemic stroke who underwent carotid endarterectomy for carotid artery stenosis. Carotid plaques were graded by two pathologists. Thrombus materials were divided into two groups: white and red. The parameters of assessment were plaque rupture, lipid core, fibrous cap thickness, inflammation, intraplaque hemorrhage, calcification, necrotic core, and neovascularization. Normally distributed data were evaluated using Mann-Whitney U and Chi-squared tests. Results: The ratio of white and red thrombus was 19.8% and 80.2%, respectively. Lipid core, plaque rupture, necrotic core, neovascularization, intraplaque hemorrhage, obstruction, and inflammation were observed more in red thrombus, which were statistically significant. Calcification and fibrous cap thickness were not statistically significant in the two groups. Moreover, intimal smooth muscle cells were present in all thrombus types. Conclusion: In our study, we found that red thrombi had more unstable characteristics than white thrombi. Thus, the risk for ischemic cerebrovascular events is more in red thrombi. However, this finding cannot be generalized due to the small number of patients in this study. Therefore, studies involving more patients are needed.
机译：目的：比较颈动脉内膜切除术患者红、白血栓的特点。材料和方法：对81例因颈动脉狭窄行颈动脉内膜切除术的缺血性卒中患者进行研究。颈动脉斑块由两位病理学家进行分级。血栓材料分为两组：白色和红色。评估参数包括斑块破裂、脂质核心、纤维帽厚度、炎症、斑块内出血、钙化、坏死核心和新生血管。使用Mann-Whitney U和卡方检验评估正态分布数据。结果：白色血栓占19.8%，红色血栓占80.2%。红色血栓中脂质核心、斑块破裂、坏死核心、新生血管、斑块内出血、阻塞和炎症的发生率更高，具有统计学意义。两组的钙化和纤维帽厚度无统计学意义。此外，内膜平滑肌细胞存在于所有类型的血栓中。结论：在我们的研究中，我们发现红色血栓比白色血栓具有更多的不稳定特征。因此，发生缺血性脑血管事件的风险在红色血栓中更高。然而，由于本研究中的患者人数较少，这一发现无法推广。因此，需要更多患者参与研究。

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