Role of the intestinal MALT in pathogenesis of the IgA-nephropathy

Guliaev Sergei V; Strizhakov Leonid A.; Chebotareva Natalia V; Moiseev Sergei V

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Role of the intestinal MALT in pathogenesis of the IgA-nephropathy

机译：肠麦芽在IGA-肾病发病机制中的作用

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摘要

Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or abnormal intestinal permeability are discussed in details. Based on supposed entero-renal pathogenesis of the disease future treatment modalities are considered. Relevant world's literature is cited.

机译：本文介绍了免疫球蛋白（Ig）A肾病发病机制的现代观点，以及与肠道MALT系统活性的可能关系。详细讨论了IgA糖基化异常和IgA肾病与肠道疾病或肠道通透性异常的相关性增加。根据假定的该病的肠肾发病机制，考虑未来的治疗方式。引用了世界相关文献。

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来源
《Терапевтичесκий архив》 |2021年第6期|共5页
作者
Guliaev Sergei V; Strizhakov Leonid A.; Chebotareva Natalia V; Moiseev Sergei V;
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作者单位

Sechenov Univ Sechenov Moscow State Med Univ 1 Moscow Russia;

Sechenov Univ Sechenov Moscow State Med Univ 1 Moscow Russia;

Sechenov Univ Sechenov Moscow State Med Univ 1 Moscow Russia;

Sechenov Univ Sechenov Moscow State Med Univ 1 Moscow Russia;

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原文格式 PDF
正文语种 rus
中图分类临床医学;
关键词
immunoglobulin A-nephropathy; immunoglobulin A; aberrant glycosylation of immunoglobulin A; intestinal permeability; MALT;

机译：免疫球蛋白A肾病;免疫球蛋白A;免疫球蛋白A异常糖基化;肠道通透性;麦芽;

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2. Role of dietary fibres, intestinal hypermotility and leukotrienes in the pathogenesis of NSAID-induced small intestinal ulcers in cats. [J] . Satoh H, Shiotani S, Otsuka N, Gut: Journal of the British Society of Gastroenterology . 2009,第12期

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3. Molecular pathogenesis of MALT lymphoma: two signaling pathways underlying the antiapoptotic effect of API2-MALT1 fusion protein [J] . M Nakagawa, M Seto, Y Hosokawa Leukemia . 2006,第6期

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Role of the intestinal MALT in pathogenesis of the IgA-nephropathy

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