• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Annual Review of Analytical Chemistry >Evolution of Orbitrap Mass Spectrometry Instrumentation
【24h】

Evolution of Orbitrap Mass Spectrometry Instrumentation

机译：Orbitrap质谱仪的发展

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We discuss the evolution of Orbitrap (TM) mass spectrometry (MS) from its birth in the late 1990s to its current role as one of the most prominent techniques for MS. The Orbitrap mass analyzer is the first high-performance mass analyzer that employs trapping of ions in electrostatic fields. Tight integration with the ion injection process enables the high-resolution, mass accuracy, and sensitivity that have become essential for addressing analytical needs in numerous areas of research, as well as in routine analysis. We examine three major families of instruments (related to the LTQ Orbitrap, Q Exactive, and Orbitrap Fusion mass spectrometers) in the context of their historical development over the past ten eventful years. We discuss as well future trends and perspectives of Orbitrap MS. We illustrate the compelling potential of Orbitrap-based mass spectrometers as (ultra) high-resolution platforms, not only for high-end proteomic applications, but also for routine targeted analysis.
机译：我们讨论了Orbitrap（TM）质谱（MS）从其1990年代末的诞生到目前作为MS最重要的技术之一的作用。 Orbitrap质量分析仪是第一款采用离子在静电场中捕获的高性能质量分析仪。与离子注入过程的紧密集成可实现高分辨率，质量准确度和灵敏度，这些对于解决众多研究领域以及常规分析中的分析需求至关重要。在过去十多年的历史发展过程中，我们考察了三大类仪器（与LTQ Orbitrap，Q Exactive和Orbitrap Fusion质谱仪有关）。我们还将讨论Orbitrap MS的未来趋势和前景。我们说明了基于Orbitrap的质谱仪作为（超）高分辨率平台的巨大潜力，不仅适用于高端蛋白质组学应用，而且还适用于常规目标分析。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号