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Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy: Expanding the Versatility of Surface-Enhanced Raman Scattering

机译:壳隔离的纳米增强拉曼光谱:扩大了表面增强拉曼散射的多功能性

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摘要

Surface-enhanced Raman scattering (SERS) is a powerful technique for detection and characterization because of its extremely high sensitivity and the rich structural information that it can offer. However, most SERS substrates are composed of Au, Ag, or Cu, and a lack of substrate generality has greatly limited the breadth of the use of SERS. Recently, we have devised a method by which SERS can be obtained from virtually any surface. Au nanoparticles are coated with ultrathin silica shells. The Au core provides Raman signal enhancement; the silica shell prevents the core from coming into direct contact with probe/analyte molecules or the surface over which these particles are spread (i.e., prevents the contamination of the chemical system under study). In the present review, we expand upon previous discussion of the enhancement mechanism; procedures for the synthesis and characterization of our nanoparticles; and applications in surface chemistry, electrochemistry, and inspection.
机译:表面增强拉曼散射(SERS)是一种强大的检测和表征技术,因为它具有极高的灵敏度和可提供的丰富结构信息。但是,大多数SERS基材由Au,Ag或Cu组成,并且缺乏基材通用性极大地限制了SERS使用的广度。最近,我们设计了一种方法,通过该方法可以从几乎任何表面获得SERS。金纳米颗粒涂有超薄二氧化硅壳。 Au核心提供拉曼信号增强;硅胶外壳可防止核心与探针/分析物分子或这些粒子散布在其上的表面直接接触(即防止污染所研究的化学系统)。在当前的审查中,我们扩展了先前对增强机制的讨论;纳米粒子的合成和表征程序;及其在表面化学,电化学和检查中的应用。

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